Homologous Vs Autologous PRP For Hair Loss
Homologous PRP Vs Autologous PRP For Hair Loss

Research suggests that homologous PRP – that is PRP prepared from pooled platelets within the same blood group as the patient – is more effective than autologous PRP – that is PRP prepared from only the patient’s own blood – for hair loss. Here’s the link to the article in Pub Med database.

If you’re a plastic surgeon and would like to try a PRP Kit for hair loss, contact us here.

NEW: Hands-On Injectables Training In Houston By Dr. Katz

Should You Be Using PRP Instead of Dermal Fillers?

The short answer – you should be using both! According to this journal article by Dr. Daniel Sister, combining Platelet-Rich Plasma with Hyaluronic Acid fillers delivers 100% success rate with enhanced results while minimizing the numbers of injections needed. And with the new DrPRP Plasma-Fill™ Bio-Filler Maker Machine, you can opt for 100% PRP fillers when patients request to go all-organic.

Here’s why this is important:

  1. PRP fillers are natural and organic: The dermal fillers produced by Plasma-Fill™ comes from autologous blood, so it’s 100% natural and over time, the product will dissolve into the blood stream without unwanted consequences.
  2. Enhanced skin rejuvenation: The growth factors contained in PRP are known to promote the production of collagen so its not only about volume but skin rejuvenation is a key result unlike synthetic fillers.
  3. Healthy skin, less blemishes: Being a healing agent, PRP adds a touch of healing into the mix so that if there are acne blemishes, excessive dryness or even minor scars, those are more likely see improvement giving the treatment a great value for money.
  4. Save patient’s money: Stocking big brand synthetic fillers can be very damaging to your cash-flow as well as your patient’s wallet. That’s why we’re seeing PRP filler adoption at a record rate. It’s a no-brainer. There is expensive and side-effects-prone artificial stuff and the organic and cheaper alternative for pretty much the same results. Even though we may have to rely on synthetic fillers for certain cases, the cases you opt for PRP fillers will offset the costs significantly.

Exclusive Hands-On Training For Physicians In Houston

Handling PRP dermal fillers is different compared to traditional hyaluronic acid fillers – for example, prp fillers need to handled at room temperature or higher at all times and they have to be injected with a different type of needle. And there’s more fine tuning to be done if you want consistent better results and patient satisfaction. That’s why we’re excited to partner with one of the best cosmetic surgeons in the field, Dr. Howard Katz to offer you the training you need to achieve mastery in this arena.


Dentox offers industry-leading Botox training around the world and is now bringing its one-day seminars to Houston. Dentox courses are taught directly by Dr. Howard Katz, whose name is on the actual patent application for Botulinum Toxins (Botox, Dysport, Xeomin, etc), and is the first educator in the uses of Botox for facial aesthetics.

The class will include complete instruction on injecting Botox and Fillers for the most popular therapeutic and aesthetic treatments available. How to avoid and correct common side effects, create truly natural results, and market your services effectively are all part of the program. For several months now, Dentox in conjunction with Dr. PRP have also included platelet-rich plasma injection training, and if responses from doctors and dentists in other locations are any indication, Houston medical professionals will be thrilled with the competitive advantage provided with the use of PRP as an injectable material.

Discover The Unique, Exclusive Dentox LIFT Procedure


Yes, you read that right. DentoX LIFT is a 30-minute non-surgical procedure that even a dentist can perform! In this training, Dr Katz will be sharing his trade secrets with you so you too can exceed your patients expectations. The DentoX lift is incredibly simple and the results stunning. You will learn how you can transform your patient’s jawline, cheekbones, lips and smile instantly with this procedure. You’ll be surprised by what you can accomplish in 30 minutes!

Invest In A Unique Training Experience

When considering whether to add platelet-rich plasma for cosmetic purposes to your medical or dental practice, it’s important to consider how you will be trained. Precision is required for a positive patient experience. Crafting and contouring is just as much art as science. Additionally, it’s important to be well-trained in managing patient expectations so they understand what’s possible and what isn’t. All of that and more is part of the new injectables program being offered by Dentox in partnership with Dr. PRP, the first of which will be held in Houston on February 24th.


With PRP instead of dermal fillers, everyone saves – and everyone benefits. The Botox training course from Dentox is built around Dr. Howard Katz and his decades of training experience. And now, it’s also building on the power of PRP to provide excellent, affordable results.

Praise For Dr. Howard Katz

Dr. Katz is one of the foremost experts in this field of facial aesthetics. He’s an inventor named on the actual patent applications for all Botulinum Toxins including Botox, Dysport, Xeomin and Myoblock. His expertise is so in-depth, there’s little doubt that this course is going to be incredibly informative for you.


Dr. Katz is not only an extremely valuable expert but he’s actually quite interesting to listen to. He has a simple way of imparting his knowledge in others – by the time you’re done with the training, you’ll actually feel super confident about the procedures you’ve learned. Don’t take our word for it, just ask previous students.

Here, watch these videos for a taste of what’s to come.


5 Ways Platelet-Rich Plasma Is Relieving Pain in America

Few things are as life-shrinking as chronic pain. Health economists report that chronic pain costs our nation more than $635 billion each year in medical treatment and lost productivity – more than cancer, heart disease and diabetes. Painkillers have been the only relief medication in modern history. That’s changing with Platelet-Rich Plasma. It has been emerging as one of the key players in pain management.

In any life that’s exclusively ruled by pain, Platelet-Rich Plasma has the power to bring back pleasure and normalcy. It’s certainly a better option for those who’re getting by on four or five Advils a day and wondering what the long term consequences would be.


First of all, Platelet-Rich Plasma injections are completely safe. The PRP, prepared by centrifuging the patient’s blood in a special blood tube, works in a two step way. First the injections, often guided by ultrasound, breaks up the tissues and second, the growth factors in the PRP helps rebuild the entire tissue. This produces a healing effect and reduces pain.

Here are five common types of pain that can be healed with Platelet-Rich Plasma.

1. Arthritis pain

It’s been well-proven that a few shots of Platelet-Rich Plasma can produce a huge effect for Arthritis patients. It has the potential to…

  • Inhibit inflammation and thus slowing down degeneration
  • Stimulate cartilage formation
  • Kickstart the production of lubricating fluid

These activities in the affected site ends up reducing the pain sensation.

As a long term effect, Platelet-Rich Plasma injections tend to preserve the joints in more than 70% of the cases – as reported by a landmark study in 2013. Recent studies have shown similar results too. They discovered that a two or three injection treatment over a period of 4-6 weeks with Platelet-Rich Plasma does more benefit that similar injection treatments with either Corticosteroids or Hyaluronic Acid. Moreover, the cartilage degeneration was significantly slowed even for patients in advanced stages of Osteoarthritis.

The researchers also conclude that repeating the injections after 6 months ensured better results.


2. Neurological pain

Platelet-Rich Plasma is one heck of a wonder treatment whose healing potential seems to be expanding everyday and seems like it’s only limited by the physician’s imagination. The latest of those new discoveries is in the field of nerve regeneration and the resulting neuropathic pain. Nerve fibers consisting of neurons are very delicate structures and not much has been discovered about its operating mechanism. But recently, platelet rich plasma have been shown to promote the restoration of nerve fibers.


In a study performed at Hasanuddin University in Indonesia, Platelet-Rich Plasma was successful in nerve regeneration for patients with leprosy peripheral neuropathy – a situation where all traditional treatments have failed. Which means PRP injections are effective in restoring sensations when it has been lost. This is remarkable news.

Then there is another study conducted in Greece the shows very encouraging mid-term results regarding PRP for treatment of Carpal tunnel syndrome.

All of this is proof that Neuropathic pain can be alleviated by Platelet-Rich Plasma. This paper by a researcher at the University of Puerto Rico analyses how Platelet-Rich Plasma has been able to eliminate neuropathic pain. He reports that PRP’s ability to promote axon regeneration is the key.

Here’s a video from a Rejuv Medical where a patient explains how she had PRP Injections for Nerve treatments and how it changed her life remarkably.

3. Chronic back pain

Chronic back pain and sciatica are mysterious conditions and physicians generally have a hard time figuring out what’s causing them. They first thing they do is to scan the lower back area for defects. When they find one, they’ll recommend surgery to correct that defect even though they have no idea if that defect is indeed the culprit of the pain. When they can’t find any defects, they end up being puzzled and sent the patient away with a bunch of Advils.

In a spine health forum, a patient explains his situation which was similar. His physician suspected the tears in L4-L5 spine segment to be the causing the pain. But there were minor tears and bulges everywhere, so the physician was confused. The patient ended up having to take 8 Advils a day. Unable to continue with that, the patient skeptically tried Platelet-Rich Plasma injections. He went from not being able to sit back in office or drive in a car (even with those medications) to stopping the medications altogether and going on a family trip overseas. Talk about a dramatic shift in life experience!

Another patient on the same forum describes how she had PRP injection for chronic pain in the cervical spine, and it’s been pain-free for two years.


These kind of stories are supplemented by occasional clinical studies like this where the patients not only had experienced near complete pain relief but also were able to sustain those results for 2 years. This is remarkable for a degenerative disease, aka, a condition that worsens as time goes by. Here are another study conducted in China and another one by Japanese researchers.

4. Joint Pain

In addition to back and knees, almost all other joints are being treated by Platelet-Rich Plasma now. As the science of PRP evolves, the treatment is vigorously gaining popularity with more and more patients demanding it from their physicians. After all, the procedure is incredibly straightforward and is easily understood by most. The physicians hardly need to talk before the patient accepts eagerly.

Hence the doctors are now quick to prescribe Platelet-Rich Plasma for any case of chronic bursitis – in areas like fingers, elbow, toes, hip, shoulders, neck, wrist, ankle, and hip – and the results are almost always positive.

In fact, Platelet-Rich Plasma can be – and must be – prescribed for more than 50% of the musculoskeletal issues that are usually treated with surgery or steroid injections.


5. Post surgical pain

Surgical pain relief is one of the newer areas where Platelet-Rich Plasma is gaining ground. This is primarily to take advantage of the wound-healing and bone regeneration aspects of PRP, but pain-relief is a very evident beneficial side-effect. Some medical perfusionists advice Platelet-Rich Plasma after almost all surgeries including Neurosurgery, Tumor removal surgery, Oral and Maxillofacial Surgery, Head and Neck Surgeries, Reconstructions and Cosmetic Surgery, Orthopedic/Spinal Surgery, Hand and Foot Surgery, Bone Graft Surgery, Cardiothoracic Surgery and Bariatric Surgery.

By cutting short the time it takes to heal from the wounds of surgery, Platelet-Rich Plasma plays a pivotal role in assisting patients get productive as early as possible. And when done in conjunction with surgery, Platelet-Rich Plasma injections are almost always paid for by the insurance provider covering the surgery.


The beginning of the end of orthopedic surgery?

At a time when big hospitals are racing towards a possible automation of orthopedic surgeries, there are some physicians who believe that the rise of Platelet-Rich Plasma together with the rise of stem cell technology marks the beginning of the end for 80% of the orthopedic surgeries. They say science is finally waking up to the fact that human intervention is not the most efficient way of dealing with musculoskeletal issues. Rather, it’s best to provide the necessarily biologics in the form of PRP and stem cells so that the body can invoke it’s own healing.


I hope you agree – because today’s regenerative medical trends are certainly pushing the medical industry in that direction.

If you haven’t started offering Platelet-Rich Plasma – or would like to know some general protocols, we would love to share them with you. Just call us at (844) 377-7787 or email via

Platelet-Rich Plasma Certification Training
5 Questions To Ask Before Offering Platelet-Rich Plasma

Almost everyone is an ideal candidate for Platelet-Rich Plasma.

PRP, with it’s more than 1 million platelets per microlitre constitution, has brought about huge relief for patients with acute joint injuries, joint pain, arthritis, torn meniscus sciatica, degenerative diseases, rotator cuff tears, ligamentous laxity… you name it. It is also injected into spinal discs for disk injection therapy, and into knee and shoulder joints for regenerative purposes.

Today, Platelet-Rich Plasma dominates fields like orthopedics, sports medicine, ophthalmology, wound healing and cosmetic enhancement.

That’s why there are 8,549 entries for Platelet-Rich Plasma in the NCBI databases. To give you a reference, acetaminophen, the #1 most prescribed drug, has about 19,741 entries.

Combining those with the fact that it’s autologous, and there’s little risk for rejection or side effects, it will seem like PRP is a universal healing agent.

Except it’s not.

There are a couple of things physicians must be careful of. Because there are times when administering PRP can be a bad decision although it’s not anywhere as complicated as a wrongly prescribed drug.

Platelet-Rich Plasma Certification Training

Here are the questions physician should ask before offering Platelet-Rich Plasma to their patients.

1. Are they free of these contraindicated conditions?

PRP happens to be one of the safest procedures out there. With PRP, you draw 20cc blood from the patient, spin it and then re-inject it to the injured area. No big deal. But as with any other injection, the basic risks of infection, pain and inflammation are still there. The blood collection, PRP processing, and activation should be done in a maximally sterile environment for the results to be accurate.

And that is if the patient is free of any of these pre-existing conditions:

  • Cancer or Metastatic disease: the blood of patients with cancer, especially hematopoietic or of bone, might be infected with the cancer cells, so PRP is not advised. Same goes for any other metastatic diseases.
  • An active local infection: if there’s an existing infection in the area to be treated, you must treat and heal the infections first before applying PRP therapy. Except for some bacterial infections which PRP’s anti-microbial properties can control.
  • Pregnant or are breastfeeding: the risk of infection (even though minor) means it’s not advised for expecting or new moms.
  • A low platelet count (thrombocytopenia): patients with platelet count less than 105/ul is not advisable since the low platelet count makes it ineffective anyway.
  • Anemia or low HGB count: patients with less than 10 g/dl of hemoglobin should not be allowed to undergo PRP as their blood may be weak.
  • Platelet dysfunction syndrome: patients with any of the five types of platelet function disorders are not recommended. It may aggravate their symptoms.
  • Antiplatelet therapy: those who are undergoing antiplatelet therapy for arterial circulation may not see any results due to lack of platelets.
  • Active Smoking Habit: smoking increases blood pressure and is said to lower platelets (not always), and so the effect of treatment may be low enough to not warrant it.
  • Alcohol Overuse: we know consuming too much alcohol can diminish body’s capacity to release stem cells so alcohol intake should be controlled or avoided before and during Platelet-Rich Plasma treatments.
  • Allergic to cows: bovine thrombin is typically the standard for initiating clotting of PRP and is derived from cows. So if the patients are allergic to cow’s products, alternatives need to be arranged.
  • Septicemia or blood infection: if the blood is infected by harmful bacteria, its effects may be amplified by doing PRP.
  • Local toxicity to Bupivacaine HCL or Lidocaine: if the patient has an allergic reaction or local toxicity to these, it could trigger an adverse reaction.
  • Corticosteroid injection and NSAIDS: patients must refrain from taking any form of corticosteroid injections for up to ONE month prior to PRP therapy. As for NSAIDS like Nurofen, Voltaren or Mobic, that period is 7-10 days.
  • Recent fever or illness: if the patient just recovered from a serious illness or fever, it may be advised to wait up to 60 days before having PRP treatment.

2. Is their condition treatable by Platelet-Rich Plasma?

First of all, the three vital factors in Platelet-Rich Plasma—growth factor levels, platelet count and activation times—will vary depending on the age and how healthy the patient is.

And so is the results. It varies from individual to individual.

Another factor to look at is the healing phase the patient is in.

Which Healing Phase Is Favorable For Platelet-Rich Plasma Treatments?

The basic mechanisms responsible for wound healing can be divided into three basic phases:

1) inflammatory

2) a proliferative phase, and

3) tissue remodeling (the longest phase).

The inflammatory phase begins immediately after a wound. This initial phase includes activation of fibrin from fibrinogen and development of a clot consisting of platelets and cross-linked fibrin strands. These platelets release a number of cytokines, growth factors and proteins that direct the wound healing.

The cytokines attract neutrophils and fibroblasts to the wound to direct the proliferative second phase of wound healing, and subsequently, attract fibroblasts which are crucial to the remodel or the third phase.

The earlier you can introduce Platelet-Rich Plasma, the stronger the effect it has on wound healing. The first two phases are obviously more favorable to the treatment because it is in those two early phases of wound healing that the cytokines and growth factors are much needed.

Which means, PRP is best administered less than 6 weeks after an acute injury before the healing slows or stops. In overuse or repetitive conditions, this time-period may be shorter.

Platelet-Rich Plasma Certification Training

That’s why we encourage physicians to use Platelet-Rich Plasma as the first-line treatment option for all healing purposes. Because, the treatment is best received in the early stages of osteoarthritis, and not only when all other options are exhausted. Our bodies naturally do that. Research shows that migration of platelets to the injured site is the first natural response of our bodies.

That being said, here are the common conditions that are known to have clinically proven benefits with Platelet-Rich Plasma treatment.

Conditions Which Can Be Treated By Platelet-Rich Plasma

Bone, Muscle And Tendon Regeneration:

If the patient’s condition will improve with bone, muscle or tendon regeneration, Platelet-Rich Plasma has a strong chance of helping. That’s why it is so popular among orthopedics. Almost all kinds of chronic tendon injuries, especially tennis elbow, Achilles Tendonitis, Rotator Cuff injuries, glenoid labral tears, hip labral tears, osteochondral lesions or inflammation of the knee patellar tendon will benefit from PRP. Even people with acute sports injuries like pulled hamstring muscles in the thigh and knee sprains benefit from it. Cartilage defects (CDs) and the most common joint disease, osteoarthritis (OA), are fantastic candidates.

And I believe every doctor has a duty to at least offer PRP to every patient suffering from these conditions, given that surgery is the only other option once conservative treatments fail.

We want to avoid surgery as much as possible.

Platelet-Rich Plasma Certification Training

Managing Healing, Recovery, and Pain:

PRP can accelerate healing and growth of bones, muscles, and tendons. So whenever there are large defects that need healing, a PRP injections can come in handy. This is true for healing after surgeries, recovery after chemotherapy, and general pain associated with age-related degeneration like back, knee and neck pain. PRP can also be used simply to improve the function of the shoulder, hip, and knees. PRP has also been used in spinal and joint fusion surgeries with success.

A skilled practitioner can administer numerous PRP injections (with varying constitutions, perhaps) depending on the severity of the condition.

Reducing aging, hair loss, and hormonal symptoms:

Platelet-Rich Plasma has become popular as a treatment for reversing aging symptoms in hands, face, neck, jawline, and décolleté including sagging jowls, thinning of the skin, puffiness, age spots, and wrinkling. Also, PRP is also considered a cosmetic medicine and is used to treat acne, scarring, eye bags, and post-pregnancy skin laxity.

The famous treatment is Platelet-Rich Plasma Facelift which is PRP combined with Microneedling where the PRP serum is directly injected into the skin through multiple tiny punctures under the dermis with or without topical local anesthesia. This stimulates the tissue and triggers a healing process; it’s the first step being a mild inflammation. The result is the production of new collagen tissues leading to a reduction of symptoms.

PRP has also shown promise to heal alopecia. It acts as fertilizer by recruiting stem cells to the hair follicles. PRP’s ability to form new blood vessels (angiogenesis) and the grow blood vessels from already-existing blood vessel tissues also helps.

Usage of Ultrasound Imaging

For PRP injections, the patient must also agree to use fluoroscopy, CT, or ultrasonography (US) for real-time visualization of the procedure.  This maximizes efficacy by guiding the needle accurately.

3. Can the patient cover out-of-pocket costs?

Platelet-Rich Plasma is still considered experimental by most insurance companies. Hence you may not be able to bill your patient’s health insurance plan for this service. However, if you’re a surgeon and use it in conjunction with surgery, PRP may be eligible for reimbursement. It’s best to ask the insurance company in advance.

Platelet-Rich Plasma Certification Training

Treatment cost can range from $200 to $2000 and in most cases patients have to bear it themselves. However, because there is no cost to actual PRP serum itself, the cost does not double or triple when more than one condition is treated. Typically the cost is calculated based on how much time it takes for the entire procedure.

Here are the insurance plans that do not cover PRP in general:

  • MEDICARE (except when enrolled in a clinical study)

4. Do We Have The Right Protocol?

Although the Platelet-Rich Plasma procedure is simple as it looks from the outside, there’s more science to it that meets the eye. As the saying goes, the devil is in the details. And it can have a huge impact on the outcome.

Here are further questions to ask in this aspect.

Do we have the right concentration and composition? For the results with PRP to be consistent, you need the right concentration and composition. A higher platelet concentration may not necessarily be better and in some cases can be counterproductive.

How does leukocyte-rich and leukocyte-poor PRP compare?  Do you know how leukocyte-rich and leukocyte-poor Platelet-Rich Plasma work for specific conditions? Leukocyte-rich PRP causes a more pronounced inflammatory effect than leukocyte-poor PRP and may be detrimental to the healing of tendons. Therefore, leukocyte-poor PRP is preferred for acutely injured tendons.

Which type of activation should we use? There are two types of activation that can release growth factors, endogenous or exogenous. But they both does not have the same results.

And which centrifuge and PRP system should we use? There are a lot of centrifuges and PRP systems in the market. It’s important that you know the criteria you need to pay attention to for the specific needs that you’ll be using PRP for.

Platelet-Rich Plasma Certification Training

5. Do We Have The Right Training?

As a physician, it’s your duty to be acutely aware of all the options you have with Platelet-Rich Plasma. And be able to determine the appropriate indication and contraindications for PRP use, consistent with ICMS/AMSSM standards. That’s why we suggest you attend a training course for extensive instructions.

Taking a proper course will also help you understand how to clearly communicate the risks, benefits, expected course, and follow-ups to the patient. This is assuming that as a physician, you already have a thorough understanding of graft selection and preparation of a graft with or without additive supports (calcium, thrombin, etc) as well as management of any complications.

Another important know-how that can come in handy for Platelet-Rich Plasma practitioners is pain management strategies.

Excellent Training On Platelet-Rich Plasma For Cosmetic Use

If you’ll be using Platelet-Rich Plasma for cosmetic purposes, here’s an excellent training that you can register for. It provides full training and CME credits for dermatological applications.

Platelet-Rich Plasma Certification Training

This Course also includes extensive Training on Using Micro-needling along with PRP. Known as the PRP Facelift and the PRP Facial, these are hottest trends in the skin rejuvenation arena. You’ll also get the latest research on the subject with dozens of citations and live links to full-text peer-reviewed articles on this subject.

If you want a one-stop training to add cosmetic PRP to your existing practice of BTX-A and Facial Fillers… this is your best bet.

And the best part is everything is online. You can take the course at the comfort of your own home.

Click here to learn more

Platelet-Rich Plasma Certification Training

Platelet-Rich Plasma For Stretch Marks
What’s True About Platelet-Rich Plasma For Stretch Marks?

Cindy is a career woman. So when she became pregnant for the first time, she was confused about which aspect of her life had higher priority – her work or taking care of her growing body. Not wanting to drown in that confusion, she kept herself busy with her work all day while snacking every little free time she had. This meant she was putting on a lot of weight, fast. Occasionally, her more experienced sister would remind her to apply Bio Oil on her growing tummy before bed, but she was too exhausted to actually do it. Except maybe for a few nights.

It wasn’t until after she delivered her baby that she realized her folly – her belly now looked like a road map.

What Works For Stretch Marks?

Sure, there are a variety of topical treatments, the ones with cocoa butter are the trend, but they’ll hardly affect severe stretch marks. They perform better when used as preventive measures. Because fully developed stretch marks are rarely skin deep. The stretching occurs on the layer underneath the surface called dermis. And the inability of the surface layer (epidermis) to keep up with the stretching is what’s causing the appearance of deep roads of stretch marks.

One way to “cure” stretch marks or at least the appearance of stretch marks is to make the skin surrounding the stretch marks a level closer to the stretch mark itself. This can be done by various minimally invasive “scarring” technologies like microdermabrasion, microneedling and CO2 fractional laser.

But You Said Platelet-Rich Plasma For Stretch Marks, Didn’t You?

Yes. But you see, platelets can only supply growth factors wherever healing is initiated. So unless healing is initiated or is still ongoing (not in the case of a fully developed stretch mark), the injected Platelet-Rich Plasma may not be able to produce it’s excellent results.

That’s why in forums you can hear a lot of advice from doctors who claim Platelet-Rich Plasma can’t help stretch marks. In fact, that’d be the first thing I’d say if someone asked me.

However, what if we could artificially initiate the healing? Not only in the outer epidermis layer, but also in the underlying dermis layer too? Now, that’s an excellent opportunity to put the growth factors in Platelet-Rich Plasma to good use, wouldn’t you agree?

Platelet-Rich Plasma For Stretch Marks

Actually that’s exactly how hundreds of thousands of happy men and women get rid of their stretch marks, around the world.

Enter PRP Microneedling

PRP microneedling is nothing but swapping Vitamin C that’s used in traditional microneedling with Platelet-Rich Plasma. This is traditionally called Platelet-Rich Plasma facial – due to the fact that you’re essentially spreading blood components over your face. This is a particularly effective treatment for the face. But it can provide even better results for stretch marks (probably the most effective treatment for stretch marks.)

Here’s why this particular combination really works:

1. Getting to the root of the situation

With micro-needling, what we’re actually doing is punching some holes on both the outer epidermis layer and the inner dermis layer of the skin. These holes are so micro that it restores back to normal within minutes or hours. However, during the time it’s open a healing response is triggered. The very act of triggering a healing response in the inner dermis layer means there’s going to be some improvement on the stretch marks – as that’s where the source is. That’s probably why doctors recommend micro-needling for stretch marks over any other treatments. The procedure also removes unwanted, half-dead cells from the outer skin causing the stretch marks to appear less deep.

2. Accelerated Healing With PRP

PRP’s job is to accelerate the healing response triggered by the micro needles, and it must do so during the time it’s open. So immediately after the micro-needling, a concentrated gel of PRP is applied. And massaged well enough for the platelets to actually seep through the holes. These platelets first stop the micro-bleeding caused by the microneedles and then the growth factors in the platelets trigger the production of a substantial amount of collagen. Now, collagen’s primary role is replacement of dead skin cells. Which means, it’ll replace all the dead, broken and torn skin cells in the entire area. The result is fresh new skin in the areas of the stretch mark causing it to actually shrink in size and look more rejuvenated.

Why Platelet-Rich Plasma?

Platelet-Rich Plasma is a powerful healing component. That’s why it was invented in the first place. In 1987, surgeons found that autologous platelet-rich plasma and red blood cell concentrates diminishes the cost of healing for cardiac surgery — meaning faster, efficient and natural healing for patients. Now, the same force that heals a cardiac surgery also can also cause rejuvenation of our body — whether it’s the skin or any other organ in the body. We’re only beginning to peel layers of healing potential found in Platelet-Rich Plasma. A 2015 chinese study about growth factors in PRP says it can even heal bones. They’re not the only ones. Here’s another study of PRP for bone grafts and they found it helps too.

So it’d be outright foolish to not use such a potent, natural healing agent for skin rejuvenation purposes. And micro-needling seems to be just what Platelet-Rich Plasma needs to exercise its healing powers. It’s much better than stockpiling tons of topical products that might “cure” stretch marks — scar creams, retinoids, and peptides.

Platelet-Rich Plasma For Stretch Marks

The More Earlier The Better

In healing, studies show platelets have much better efficiency when they are introduced right after the wound initiation. The same is the case for stretch marks. As soon as you see those marks, it’s better to head straight to the clinic and get a Platelet-Rich Plasma + Micro-needling session to heal it. The longer you wait, the more harder it gets to wipe them off. So stop experimenting with topical creams – they’re meant to be used as preventive measures.

Here’s a video from The Doctors show about the procedure.

The video talks about Megan who had unusually worse scars and stretch marks as a result of pregnancy and multiple surgeries. After dabbling with a couple of topical creams, laser therapy and microdermabrasion, she was quick enough to see the virtue of micro-needling combined with Platelet-Rich Plasma. The video is about her 4th treatment and so far the results look amazing. Her doctor, Dr. Semira Bayati, says her quick decision to switch to PRP is what made the treatment effective.

Platelet-Rich Plasma Vs Platelet-Rich Fibrin
The Growth Factor Showdown: Plasma Vs Fibrin

Yep, it’s Platelet-Rich Plasma. There has been numerous speculations about which one among the latest Platelet-Rich family was the greatest—is it the plasma or the fibrin or even latest the A-fibrin? That confusion is somewhat over now.

Platelet-products are known to facilitate angiogenesis, hemostasis, osteogenesis, and bone growth. But see, the only reason plasma can do that is because of the growth factors it carries. Let’s review the specific roles of these growth factors in the healing process.

Growth Factors In Platelet-Rich Plasma

These are growth factors that are traditionally known to have played a vital healing role in PRP. If you’re seeing your patients get better as a result of that injection you gave, these are guys you need to thank for.

Platelet-Derived Growth Factor (PDGF): Regulates cell growth and division. Especially in blood vessels. In other words, this guy is the reason the blood vessels in our body reproduces.

Transforming Growth Factor Beta(TGF-b): Responsible for overall cell proliferation, differentiation, and other functions.

Fibroblast Growth Factor (FGF): Plays a vital role in the wound healing process and embryonic development. Also behind the proliferation and differentiation of certain specialized cells and tissues.

Vascular Endothelial Growth Factor: Responsible for vasculogenesis and angiogenesis. Restores oxygen supply in cells when inadequate. It also helps create new blood vessels after injury.

Keratinocyte Growth Factor (KGF): Found in the epithelialization-phase of wound healing. In other words, it causes the formation of epithelium immediately after a wound or injury occurs.

Connective Tissue Growth Factor: Major functions in cell adhesion, migration, proliferation, angiogenesis, skeletal development, and tissue wound repair.

These growth factors are what enables a Platelet-Rich product in tissue regeneration.

Platelet-Rich Plasma Rules

However, this new study suggests Platelet-Rich Plasma and it’s gelled cousin Platelet-Rich Fibrin both differ in the release of these growth factors which can significantly affect the healing outcome.

Here’s the takeaway:

“The advantage of PRP is the release of significantly higher proteins at earlier time points whereas PRF displayed a continual and steady release of growth factors over a 10-day period.”

Some argue that PRP enriched with large number of growth factors (a portion of it may even be excess) produce short-term effect and so is less desirable than a PRF whose release is slower and thus more beneficial in the long run.

That being said, PRF do have some advantage over PRP. Mainly:

  • It doesn’t need thrombin and anticoagulants.
  • It results in better healing due to its slow polymerization process.
  • And it helps in hemostasis.
How Platelet-Rich Plasma Differs From Platelet-Rich Fibrin

Platelet-Rich Plasma is a result of double spin method — a hard spin to separate red blood cells from everything everything else in the autologous (or whole) blood and a soft spin to separate the platelets and white blood cells. The result is Platelet-Rich Plasma (PRP), Platelet-Poor Plasma (PPP) and Red Blood Cells.

PRF is a newer method. Here after the first centrifugation, the middle layer is taken—which contains less platelets but more clotting factors. This gradually forms into a fibrin network and traps in the cytokines. It is then centrifuged in a PRF centrifuge resulting in PRF, a fibrin layer containing platelets and plasma.

What Matters In Healing

Obviously, when it comes to accelerating healing, immediate availability of growth factors and cytokines matter. So I believe PRP does a better job in this than PRF. Also the immediate release of growth factors for PRP means we can repeat the PRP injections for more healing factors just days after initial injection.

Platelet-derived products are in it’s infancy now. However, considering the huge potential benefits, there’s still a lot more research to be done. How about you? Which of these do you find beneficial?

If you’re a physician using any or both of these, do write to us and let us know of your experiences. Use the contact form here.

cortisone and platelet-rich plasma injections
Cortisone & Healing: The Bad Marriage Ends—New Study Reveals Successor

In 1950, Kendall, Hench, and Reichstein received the Nobel Prize for Physiology and Medicine for their discovery of cortisone. No doubt, it was a great step forward in our knowledge of the hormones of the adrenal cortex and their uses in medicine.

Today, cortisone shots is a leading Anti-inflammatory drug given to relieve pain and inflammation, especially for joints—ankle, elbow, hip, knee, shoulder, spine and wrist.

The thing is, even the people who discovered it, knew cortisone is like insulin—it works only so long as it is given to the patient. And more cortisone actually accelerates degeneration of the soft-tissue in the joints. Even though doctors now limit cortisone injections to 3-4 times a year per patient, it’s still causing harm by pulling the plug on body’s own healing mechanism.

Plus, the entire medical community knows that inflammation is a prerequisite for healing. We had briefly discussed this topic before in our blog, but it’s so important a topic that every time there’s a new study against Cortisone, I’m compelled to write.

The #1 Culprit For Joint Replacement Surgeries

Us, Americans do at least a million joint replacement surgeries every year. And one thing that runs common among all who’re having these surgeries is that almost all of them have had Cortisone shots in the past. In fact, Cortisone injections degenerate the joint so fast that joint replacement is inevitable for those who have them repeatedly.

And the #1 reason why people still get a cortisone shot? It’s covered by insurance. And, that way they can make the most of their insurance policies. But eventually, they get a free joint replacement surgery as a bonus too.

Platelet-Rich Plasma Injections: A Superior Alternative?

Latest research confirms Platelet-Rich Plasma as a worthy successor of Cortisone. Here in this research, Cortisone and PRP are compared side-by-side for treating Plantar Fasciitis. 60 heels with intractable plantar fasciitis were given PRP and Cortisone at 3, 6 and 12 months. Immediately after both treatments, patients with Cortisone was only marginally better than the patients with PRP. But in the long run, PRP crushes Cortisone completely. At 12-months, AOFAS score for Cortisone group was 88.5 compared to 75 for the PRP group (the lower the better).

This is the latest in a series of studies showing up over the years showing why PRP is better than Cortisone. Last year, Fox Valley Orthopedics’ Dr. James Sostak appointed PRP Injections as a successor to Cortisone for Tennis Elbow injuries.

“Tennis elbow is an excellent candidate for PRP treatment,” says Dr. Sostak. “A great deal of research suggests that PRP is superior to cortisone treatments, providing better pain relief, faster functional recovery, and helps the damaged tissues to heal.”

Naturally, Cortisone Hates PRP

Cortisone is no doubt powerful. When combined with PRP, it simply overpowers the effects of PRP. Because Cortisone pulls the plug on all healing activities of the body—including the recruitment of immune cells and stem cells. It’s like taking the batteries out of an alarm clock because it’s beeping while ignoring the fact that you’re late.

Hey, we can do better than that. Platelet-Rich Plasma not only accelerates healing, but also induces growth in ligaments, tendons and even cartilages. Plus, it boosts collagen, making skin appear remarkably better.

Platelets A Must For Wound Healing

The growth factors and stem cells that Platelet-Rich Plasma brings to the table are absolutely necessary for healing. Without them, our bodies simply can’t heal. All we’re doing with a PRP Injection is making them available in plenty. So the ligament, the tendon, the knee meniscus, spine disc, or any other sports injury area can be healed quickly.

PRP In Addition To Other Treatments

The wonderful thing about PRP is that it can be used with almost all other remedies other than Cortisone. It can be used with stem cell procedures, physiotherapy, or any other healing modalities that actually enhance healing instead of inhibiting it. This makes PRP a multi-potential blessing—soon it’s going to be a default healing shot for all kinds of injuries.

Why Tender Tendons Respond Well to PRP Therapy

Quality of life is often seriously impaired when people suffer from chronic joint or tendon pain. Repair of the chronic condition and reduction or elimination of its associated pain are the goals for physicians who treat these injuries. Health care researchers and medical providers are constantly working to develop therapies that are effective in stimulating the healing process. Tendons are notoriously hard to treat for a number of reasons. Unfortunately chronic and acute tendon injuries are among the most common physical ailments afflicting patients of all ages.

How healing works

How our body heals itself naturally

Understanding how the healing process works is a key factor in designing therapies for tendon injuries. Blood is a liquid within which are suspended solid particles of organic matter. The organic matter consists of platelets, which, in turn, contain hundreds of proteins called “growth factors”; growth factors play an important role in the healing process.

Internal and external wounds need blood flow to heal. Areas of the body that don’t have good blood flow are negatively impacted by an injury because they don’t have the fundamental aspect that stimulates the healing process. Tendons typically have limited blood flow – the Achilles’ tendon gets its blood supply from a single vessel. Aging can cause restriction of blood vessels, and constant use can cause minute tears that result in scar tissue, also restricting blood flow.  Reduced blood flow means fewer healing factors are delivered when the tendon suffers an injury.

Every wound in the body heals through a carefully balanced and timed healing process. Wounds that demonstrate poor or limited healing are thought to have failed to progress  through the normal healing stages. Local factors (those that are directly related to the wound itself – bacteria, foreign matter, etc) and systemic factors  (those that affect the overall health of the individual – diabetes, obesity, etc.) can cause impaired healing.  Both local and systemic conditions can cause restriction of blood flow to an injured area of the body, and decreased blood flow will impact the ability of the body to heal that injury.

Understanding PRP Therapy

The theory behind PRP therapy is that it will assist to heal injuries that have reduced blood flow by introducing into those sites the very blood factors that contribute to the healing process. The PRP serum is derived from the patient’s own blood. Blood is first drawn from the body, then run through two centrifuge cycles to isolate out the platelet-rich plasma and other healing factors from the platelet-poor-plasma. The final serum is then injected back into the site of the injury. Because it is of the body itself, there is no risk of rejection.

Despite the significant anecdotal evidence that PRP is effective, the medical community has yet to declare definitively its efficacy one way or the other. The biggest challenge to widespread acceptance appears to be the lack of consistent, reliable and controlled studies. Factors that can influence the effectiveness of PRP treatment include:
– The area of the body being treated;
– The overall health of the patient, and
– Whether the injury is acute (such as from a fall) or chronic (an injury developing over time).

The lack of research available on these subjects precludes any definitive conclusion from being drawn at present. Many physicians has suggested that the simple injection of a needle into the damaged tissue may be the trigger for improved healing, and not the substance being injected.

Because it poses no rejection risk, is based on medical research regarding the nature of the healing process, and is simple and quick to deliver, for those patients who suffer with chronic tendon pain, PRP therapy may provide the relief they are looking for. And who doesn’t want relief from constant, chronic pain?

To learn how to prepare Platelet-Rich Plasma using Dr.PRP Kit, click here to watch video.

PRP treatments for thinning hair
Why More Women Seeking PRP Treatments for Thinning Hair

The majority of hair growth procedures and at-home products are marketed toward men, capitalizing on middle-aged anxieties over premature balding. But in recent years, a number of women–both young and old–have pursued restorative therapies and surgeries to attend to their own thinning manes. Medical and cosmetic practices are picking up on the PRP trend, utilizing the versatile therapy to deliver promising results for ladies looking for a thicker, fuller head of hair.

PRP Treatments For Thinning Hair In Women

“A lot of women have thinning of their hair, which they are not happy, as they age.” says the country’s top dermatologist Dr. Jeffrey Rapaport, MD. in an interview with Real Self. And most of them are hereditary it seems.

Jeffrey says it’s like “rolling a rock up the hill.” You must do something proactively before it happens otherwise it’d be harder. Nowadays, there’s a surgical otion where they’ll transplant your scalp with hairs. Or you could get anti-DHT stuff which in long term causes some side effects in women.

But according to Dr. Rapaport, PRP is a game-changer. He says, “we’ve been doing that in our office for about 6 months and we’ve been getting excellent, excellent results.” He adds that PRP treatments are especially effective for cases of androgenetic alopecia (female pattern baldness).

Dr. Rapport Explains Why PRP Treatments Are Not Popular

Even though PRP has been used for years in orthopedics, sports medicine and cosmetic surgeries, it hasn’t been getting much mainstream exposure. That’s because of nothing but economics. “No one has done double blind studies because, right now, there really is no drug company that’s going to take this on because there’s no profit motive for them,” says Dr. Rapaport.

Yet, scrores of women are attracted to the non-surgical option they find in platelet rich plasma treatment, as it allows them a preventative or restorative supplement to their existing hair maintenance routines. Despite the lack of press, women have been seeking cures for their thinning locks for years, attempting laser therapies, topical solutions, supplements, changes in diet, among other sometimes effective remedies. A brief look at the hair loss industry proves men have access to more medical options than women, and their treatments have yielded overall better results.

Here’s a Video of a Woman’s 8th PRP Treatment:

This woman writes, “My goal at this point is really just to slow the progression (and I do know it will keep progressing no matter what) and keeping the shedding at a reduced state. The fact that my hair is looking fuller , softer and a bit healthier is really a bonus for me, and something I’m very happy about! I’ve communicated with many women who have had this done, many have felt it has been an amazing and beneficial thing in their lives, and others found it did’t help at all – and that’s the way it will always be with any hair loss treatment.”

The social ramifications of hair loss, unfortunately, are much more significant for women than for men. PRP has brought ladies from all over the world to a few select American practices that specialize in the treatment, and they fly in for just a brief hour long therapy session right in the doctor’s office. In a recent New York Times article, Florida-based physician Dr. Joseph Greco claims to see improvement in about 80% of his patients, and the majority of those seeking the therapy are women.

How Does PRP Work for Women’s Hair Growth?

The procedure stimulates the skin, scalp and hair follicles on the head, helping dormant strands surface for a fuller, more abundant look. Once in the office, the doctor will draw the patient’s blood, spin it in a centrifuge to extract nutrient-rich platelets, and prepare the plasma for injection. Women receive local anesthesia to numb the pain, and the healthy mixture is injected across the scalp. There are no major side effects, and patients normally leave the office and see palpable results within a month. Some women seek the PRP procedure as often as every 3 to 4 months, as doctors have seen improved hair regeneration with regular treatment.

For women, the safe and natural alternative to more invasive surgeries, which have historically low performance in female subjects, is a godsend. PRP’s stimulation of stem cells in the hair follicle has actually shown better results in women than in men, which experts say is related to hereditary factors. Dr. Carlos Wesley, a Manhattan hair restoration surgeon, says he has observed an 83% increase in female patients, something he attributes to his practice’s debut of the treatment.

What Are The Causes of Women’s Hair Loss?

Female patients seeking PRP Treatments experience hair loss due to a array of reasons, and they go well beyond the natural effects of aging. Practices offering PRP treatments see women with hair loss related to:

  • Hereditary factors
  • Pregnancy
  • Menopause
  • Stress
  • Hormone imbalance
  • Chemotherapy treatments for cancer
  • Thyroid disorders
  • Anemia
  • Autoimmune diseases
  • Psoriasis and other skin conditions
  • Damage from chemicals, dyes, and heat styling tools
Diversify Your Practice to Meet the Needs of Female Patients

Dermatologists and other doctors are experiencing great female interest in their services when incorporating PRP treatments for thinning hair. Popular hair restoration drugs on the market are not approved for women because of their specific hormonal makeup. Simply put, the industry caters less to women because severe sufferers are few and far between compared to men. But for the millions of ladies who endure progressive or overnight hair loss, the impact is devastating. Women seek cosmetic procedures much more enthusiastically than their male counterparts, and when it comes to their flowing locks, there’s no price tag on beauty.

To learn how to prepare Platelet-Rich Plasma using Dr.PRP Kit, click here to watch video.

PRP Injections — The Physician Spotlight

Five years ago, if a doctor had offered you “PRP Injections,” you probably would’ve backed away fearing if the doctor is about to do some crazy experiment that could go wrong. This miracle of a treatment went from totally strange to a healing necessity in just a few years’ time, and you probably want some answers as to why this happened.

PRP injections are like a switch that turns on healing. Whenever a chronic injury happens, bleeding causes blood flow to slow down in the immediate surrounding tissues. That’s why healing is slow. We could supply blood to compensate for the situation. But PRP injections take it a level further. They extract the natural healing components in the blood and supply them to the affected area in bulk.

Sports professionals love it because it gets them back in the game in record time. People suffering from pain (from injuries) love it because it allows them to get off the harmful painkillers fast.

A Lot Of Healing For A Lot Of People

The National Center for Biotechnology Information (NCBI) has logged over 5200 entries of Platelet-Rich Plasma (PRP) treatments ranging in medical fields from orthopedics, dermatology, otolaryngology, cardiothoracic, sports medicine, dentistry, ophthalmology, neurosurgery, urology, wound healing, urology, and maxillofacial surgery.

The early popularity of Platelet-Rich Plasma grew from the promise it was a natural and safe alternative to surgery. PRP supporters endorsed the treatment as an organic based therapy that enabled the use of one’s own plasma growth factors, to heal the body. In recent years, technology and scientific research has provided a new perception on platelets. Studies indicate that platelets have a copious amount of cytokines and growth factors that affect inflammation, infection, wound, osteogenesis, avert postoperative blood loss, soft tissue and muscle tear healing.

Scientific research now shows that platelets release several bioactive proteins that are responsible for attracting osteoblasts, macrophages, and mesenchymal stem cells, which promotes the removal of disintegrated and necrotic tissue, and also enhances tissue restoration and healing.

The interesting this is how the acceptance of PRP actually grew. In the 1990s, when medical practitioners who were predominantly trained in using prolotherapy, started using Platelet-Rich Plasma, they started to see much better clinical results when they swapped their usual injectible solution with a concentration of the patients’ own blood. Even though the PRP method is ominously more multifaceted and necessitates additional laboratory equipment to perform successfully, the reasonably more vigorous response, less treatments and enhanced tissue health that paralleled the effects of prolotherapy, made the treatment a preferred choice for them.

PRP Injection

Physician Accreditation: Platelet Rich Plasma (PRP) Injection Therapy Guidelines

First, it should administered by allopathic or osteopathic physicians with a valid license to practice.

Second, they should have prior experience treating patients successfully and safely with PRP.

Third, the doctor should adhere to ICMS/AMSSM guidelines for the handling and delivery of PRP.

Physicians who have a valid license and practice medicine and/or surgery in the state they are licensed to practice in. To successfully and safely perform PRP procedures, they require the knowledge of the following:

  • Diagnosis
  • Standard treatments
  • Benefits
  • Risks
  • Contraindications
  • Methods of preparation
  • Delivering it to the right patient in the correct situation

Here are few key things to keep in mind.

  • According to ACGME standards all physicians who give PRP injections must be board certified and retain applicable overall musculoskeletal specific continuing education credits. Topics explicitly encouraged include the following: diagnosis, treatment, and structural and radiological findings in patients with acute or chronic pain.
  • For neuro musculoskeletal injuries there are specific CME (continuing medical education credits) accredited courses that offer updated findings, techniques, and uses of PRP that physicians and surgeons are strongly encouraged to attend.
  • Physicians and surgeons who do PRP injections need be acquainted with the peer review literature and the normal treatments of the diagnoses he/she are considering for PRP therapy as well as the benefits, any risks, and the methods of PRP injections, while adhering to the specific ICMS /AMSSM guidelines of the handling and the delivery of PRP.
  • PRP training attendance will cover the preparation and proper use of grafts by a physician or a surgeon comfortable performing the PRP therapies. It is recommended that all appropriate conventional treatment measures have been exhausted to both the physicians’/surgeons’ and the patient’s satisfaction preceding the use of PRP as a treatment.
  • The physician/surgeon must be able to determine the applicable indications and contraindications for PRP treatment, consistent with standards set forth by ICMS/AMSSM. The physician/surgeon must articulate the appropriate benefits and risks of the procedure, follow-up and acceptable activities for the patient.
  • The physician must have the proper understanding of the proper graft selection and preparation of a graft with and/or without additive support such as (thrombin, calcium, etc).
  • The physician/surgeon must be educated in the recognition and management of any possible complications.
  • The physician/surgeon must be trained and comfortable with the use of pain control measures.
  • The physician/surgeon should be trained in both guided and non-guided PRP injections. Including the efficacy and safety differences of guided and non-guided injections although adherence to guided injections is the universal standard with PRP injections. Physician ability and the patient’s preference may modify the choice on a case by case basis.
  • Proven use of Cat Scan or fluoroscopy privileges will be adequate for use with PRP. American Institute of Ultrasound Medicine (AIUM) certification for ultrasound guidance is also adequate. If AIUM accreditation is absent, the doctor/surgeon must have a MINIMUM of at least one high quality ultrasound course and one advanced ultrasound course with specific training in procedures and require needle guidance.
  • Additionally, an appropriate amount of accomplished injections that shows the physician can consistently, safely and successfully place a needle in the precise structure without causing any damage to any vital nearby structures is essential.
Lack Of Insurance Payout Is The Last Hurdle

Sadly, a lot of insurance companies are holding off from covering PRP Injections.

To them, PRP sounds trouble. If a treatment as fast, convenient and side-effects-free as PRP, naturally everyone will get it. And it skyrocket the cost of coverage.

Here’s a list of insurance companies that do not cover PRP Injections.


Since you’re going to pay for the treatment, you want to be exercising the utmost care in choosing the right physician to do it. Experience helps and knowing which conditions will not benefit from PRP is important.

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