Twelve percent of women of childbearing age in the U.S. have difficulty getting or staying
pregnant.1
With more women delaying childbirth until later in life, ovarian insufficiency has become a rising
problem.
Infertility can present emotional, mental, and financial challenges both for the patient and her
partner. The challenge for the physician is helping the patient find safe and effective treatment
options with minimal invasiveness and side effects.
The current options for achieving fertility in women with ovarian insufficiency include:
- Synthetic hormone treatment
- In vitro fertilization using donor eggs
However, many women aren’t comfortable with the side effects of hormone treatment which
include increased risk of cardiovascular disease and breast cancer.2
Many women are also unable to afford the expense of in vitro fertilization or are uncomfortable
with the necessity of using donor eggs.
Ovarian rejuvenation through platelet-rich plasma (PRP) is showing promise as a safe and
effective therapy to support fertility.3
Regenerative Medicine in Fertility Treatments Webinar
- Dr. Stephan Gordts - Gynaecologist - Life Expert Center
- Dr. Rudi Campo - Fertility expert - Life Expert Center
- Sonia Herraiz, PH.D. - Ovarian Rejuvenation and Fertility Preservation
- Lucía De Miguel Gómez, PD.D. Student - at IVI RMA GLOBAL
-
Dr. Anita Van Domselaar - Co-Founder Benorm, Regenerative Medicine Specialist, Certified
Interventional Pain Sonologist, Anesthetist, Life Expert Center
Platelet-Rich Plasma to Treat Infertility
Platelet-rich plasma, or PRP, is gaining traction as an alternative treatment
option for infertility. PRP may use the body’s own natural healing process to help
regenerate damaged ovarian tissue.
But how does it work? PRP stimulates the body’s innate healing cascade.
When we experience an injury, our body responds by delivering a rush of platelet cells. When these
platelets are activated, they release several types of growth factors, proteins, and cytokines
that play a fundamental role in cell regeneration and tissue healing.
But PRP takes the natural healing response one step further by separating
platelets from other blood components and concentrating them. This specially prepared
platelet-rich plasma contains 5 to 10 times the concentration of platelets found in whole blood.
The concentrated PRP is then delivered into the ovaries via injection using an ultrasound-guided
or laparoscopic-assisted approach.4 The delivery of the
concentrated platelet-rich plasma stimulates and significantly strengthens the body’s
healing response within the ovaries.
Intraovarian PRP injection has been shown to aid a menopausal woman in becoming pregnant.6
Ovarian PRP treatment also may have helped restore menstruation in three women who hadn’t
had a menstrual cycle in over a year. These women also achieved pregnancy via natural conception
within a year after PRP treatment. The women also showed:
- Improved hormonal profile
- Decreased follicle-stimulating hormone (FSH) levels
- Increased anti-Müllerian hormone (AMH) levels7
Since PRP is an autologous therapy, using the patient’s own blood product, there is no risk
of cross reactivity or immune reaction.
THE PRP PROCESS
To create a platelet-rich plasma preparation, the following steps are performed:
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A small sample of blood is drawn from the patient and injected into the Dr. PRP blood tube.
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The platelets are then separated from the other blood components and their concentration is
increased using the Dr. PRP centrifuge and removing some of the plasma.
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The resulting platelet-rich plasma is then injected into and around the affected areas of
concern..
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The concentrated growth factors contained in the plasma trigger a mild inflammatory response
which effectively jump starts the body’s own natural healing response.
The entire process takes approximately one hour, including preparation and recovery time. For a
complete demonstration of each step of the process, view our instructional video.
DR. PRP
The Dr. PRP is an FDA-cleared medical device, holding the esteemed 510K clearance, meticulously
designed to prepare patients' blood for PRP therapy quickly and efficiently.
Our patented design creates high-concentration and high-quality platelet-rich plasma that can be
used as the physician deems necessary. This can result in tissue regeneration at the injured or
diminished site, effectively accelerating normal healing processes.
REACH OUT TO LEARN MORE
BENEFITS OF DR. PRP
SAFETY
- Completely closed, sterile system.
- Outside air is blocked with a double safety cap.
-
Since the processing is completed within the closed system, there is no risk of the PRP becoming
contaminated.
EASY TO USE
- Each kit comes pre-packaged.
- The clear chambers ensure that you can see all the components of the blood sample.
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The buffy coat layer is easily seen in the neck of the device, allowing for precise separation
of the components into the type of PRP desired.
- Red Blood Cells can even be eliminated from the final PRP product.
QUICK AND CONVENIENT
- The closed system allows for more treatments in less time.
- Customize your final PRP composition for use in different situations.
-
The PRP can and should be administered as soon as it is prepared with our kit – no
advanced preparation is needed.
HIGH CONCENTRATION
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One kit holds 20 cc of fluid (3 cc of anticoagulant + 17 cc of whole blood) and produces 4 or
more cc of highly concentrated PRP.
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The platelet recovery percentage of Dr. PRP is higher than the minimum recovery percentage of
other similar products from our competitors.
CONSISTENT RESULTS
-
Platelets require red and white blood cells to survive long-term. Unlike gel separators that
capture the platelets within the gel, our kit allows you to accurately create consistently
efficient PRP at the concentrations you want.
QUALITY
-
Our kit can recover over 90% of platelets from a blood sample to produce the highest quality
PRP.
FDA 510K CLEARED
- The kit is now proudly holding the FDA 510K clearance.
PATENTED DESIGN
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According to the ISO 13485, our kit is made with a thorough gamma-ray sterilization system.
- Made only with biocompatibility-certification completed raw materials.
TRAINING & SUPPORT
- One-on-one, in-service training is provided via GoToTraining, FaceTime, or zoom.
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User Manual with photos and descriptions detail how to use your new product, as well as
information on PRP and test results.
-
Enroll in our
Platelet-Rich Plasma CME Certification
course where you can learn cosmetic applications of PRP, including the PRP Facial and PRP
Facelift.
MARKETING SYSTEM
-
Order marketing materials and educational brochures for your patients. These brochures explain
various applications of PRP, such as sports medicine and hair regeneration.
- Add your contact information and location to our Directory of PRP Providers.
To view and order Dr. PRP kits and centrifuges, visit our
online store.
For questions and to discuss our products in more detail, contact us today at
844-377-7787 (DR- PRP-US).
References
-
“Infertility FAQs” Centers for Disease Control and Prevention. Accessed
24 June 2021.
https://www.cdc.gov/reproductivehealth/infertility/index.htm
-
“Primary ovarian insufficiency” Mayo Clinic. Accessed 24 June 2021
https://www.mayoclinic.org/diseases-conditions/premature-ovarian-failure/diagnosis-treatment/drc-20354688
-
Petryk Nataliia, Petryk Mykhailo. “Ovarian Rejuvenation Through Platelet-Rich Autologous
Plasma (PRP)-a Chance to Have a Baby Without Donor Eggs, Improving the Life Quality of Women
Suffering from Early Menopause Without Synthetic Hormonal Treatment.”
Reproductive Sciences. 2020 Nov;27(11):1975-1982. doi: 10.1007/s43032-020-00266-8.
Epub 2020 Jul 22. PMID: 32700285.
-
Petryk Nataliia, Petryk Mykhailo. “Ovarian Rejuvenation Through Platelet-Rich Autologous
Plasma (PRP)-a Chance to Have a Baby Without Donor Eggs, Improving the Life Quality of Women
Suffering from Early Menopause Without Synthetic Hormonal Treatment.”
Reproductive Sciences. 2020 Nov;27(11):1975-1982. doi: 10.1007/s43032-020-00266-8.
Epub 2020 Jul 22. PMID: 32700285.
-
Konstantinos Sfakianoudis, Mara Simopoulou, Nikolaos Nitsos, Anna Rapani, Athanasios Pappas,
Agni Pantou, Margarita Chronopoulou, Efthymios Deligeoroglou, Michael Koutsilieris, and
Konstantinos Pantos. “Autologous Platelet-Rich Plasma Treatment Enables Pregnancy for a
Woman in Premature Menopause.”
Journal of Clinical Medicine. 2019 Jan; 8(1): 1. doi: 10.3390/jcm8010001. Published
online 2018 Dec 20. PMID: 30577435
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Konstantinos Pantos, Mara Simopoulou, Agni Pantou, Anna Rapani, Petroula Tsioulou, Nikolaos
Nitsos, Stephen Syrkos, Athanasios Pappas, Michael Koutsilieris, and Konstantinos
Sfakianoudis. “A Case Series on Natural Conceptions Resulting in Ongoing Pregnancies in
Menopausal and Prematurely Menopausal Women Following Platelet-Rich Plasma Treatment.”
Cell Transplantation. 2019 Sep; 28(9-10): 1333–1340. doi:
10.1177/0963689719859539. Published online 2019 Jul 4. PMID: 31271054