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New players have entered the regenerative medicine stage. While the regenerative power of platelets is increasingly being recognized due to the success of platelet-rich plasma (PRP) treatments in medical aesthetic and orthopedic practices, innovations like PRF and PRFM are emerging with new practical applications.
Platelet-rich fibrin, known as PRF, has received a great deal of attention the last couple of years, as a second-generation platelet concentrate. Some claim it is better than PRP. Here at Dr. PRP USA, we support both options – believing that each has its own place in the field of regenerative medicine.
The more important question to ask – as with PRP – is this: “How can you get the best PRF?” It is not an easy question to answer. For years now, Dr. PRP USA has been compiling reports comparing various PRP kits on the market – because not all PRP kits are created equal.
The same can be said when you are seeking the best options for PRF. So, Dr. PRP USA is unveiling the first in a series of comparison reports for PRF. In this report, we will compare the PRF potential of two systems: Dr. PRP USA vs. EZ PRF.
PRF therapies enhance the healing process by extracting the platelets and combining them in a platelet concentrate that is biocompatible with your cells. The resulting compound contains large amounts of growth factors, stem cells, and other essential cells needed for bone healing, hair growth, and other regeneration.
Like PRP, PRF utilizes the patient's own blood and a centrifuge, but the processing method differs. PRF is obtained by centrifuging the blood without anticoagulants. What results is an autologous blood product in the form of a fibrin clot containing regenerative platelets.
Without an anticoagulant, PRF forms a fibrin matrix gelatinous clot in the test tube. This fibrin matrix helps confine growth factor secretion to the injection site. Research also indicates that fibroblasts reorganize this fibrin matrix to promote collagen synthesis.
The centrifugation speed is also much lower than that used for PRP, which is thought to protect cells from damage.
With PRP, the concentration of platelets is much higher, with removal of stem cells, white blood cells and red blood cells sought. PRF is different in that it maintains a steady leukocyte count helpful in providing other benefits when it comes to tissue and bone regeneration.
So how do you compare different systems for PRF production? Clearly, an issue like which anticoagulant is used is no longer a consideration since anticoagulants are not used at all in the creation of PRF. So, our comparison charts for PRF will look a bit different – focusing on other priorities and capturing different measures of excellence.
Some things don’t change, though, like how long the business has been in operation and if the medical devices used to create PRF have received FDA 501(k) clearance. Those issues continue to take center stage in any comparison report.
94-97%
Able to produce low or high concentrations of platelets for different applications.
No specific measure provided
2-8X
Volume Dependent
Manipulatable with DUAL spin method for increased concentration.
No specific measure provided
Standard Centrifugation - The same Dr. PRP kit you use to prepare PRP can be used to create PRF. So, you can offer both to your clients.
EZ Minispin device which can only use 13 ml tubes and cannot be used
5-8 minutes (for PRF protocols)
5-8 minutes
20 cc kit
13 ml tubes only
Yes
No
You eliminate external contamination due to the closed system, double O-ring interference port. The close chamber system offers very little contamination risk. Each kit is gamma-irradiated as per industry standards.
Information not available.
Uses a Standard Centrifuge for 50 or 60 cc tubes, depending on centrifuge and rotor.
EZ Minispin device which can only use 13 ml tubes – cannot be used for PRP.
Every Dr. PRP USA Plasma Separation Kit comes with a Dr. PRP Tube and 2 cc anticoagulant (for making PRP, not used for PRF). Dr. PRP USA offers 30 days of complimentary support during normal business hours.
Additionally, Dr. PRP USA offers an Accessories Pack which includes: one 20 cc syringe, one 10 cc syringe, one 5 cc syringe, three 18 gauge needles, one 18 gauge butterfly needle, one tourniquet, one band-aid, tape, alcohol swab, and a 2x2 gauze.
Offers two kits, the EZ2K, which contains 2 x 13 ml tubes for 3 to 6 cc of blood concentrate, and the EZ4k, which contains four tubes of 13ml and will yield up to 10cc.
Information not available.
10+ years
Information not available.
Dr. PRP USA’s Kit for producing the highest quality PRP and PRF offers transparent pricing, FDA 510(k) Clearance, the option to create both PRF and PRP, equipment compatibility and versatility, years of experience – and more! From a side-by-side comparison of the criteria above, it should be clear the Dr. PRP USA kits for PRF come out on top.
Discover what the Dr. PRP USA difference can mean for you and your practice. For medical suppliers or medical providers interested in learning more about the Dr. PRP USA line of PRP/PRF kits, you may reach the company directly at 844-377-7787.