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Posts Tagged : PRP Injections

Doctors-Ditching-Steroids-For-Platelet-Rich-Plasma-PRP-Injections
Why Doctors Are Now Ditching Steroid Injections For PRP

The use of immunosuppressive biologics, non-steroidal drugs (NSAIDs) and corticosteroids, collectively known as Anti-Inflammatory Therapeutics (AIT), has been rebuked by many, including well-known MDs. But there are, still, a good majority of family doctors, pain-management specialists, and orthopedic surgeons who routinely prescribe them for arthritis, tendonitis, and bursitis because apparently, there’s no other better alternative. This is evident in the ballooning anti-inflammatory therapeutics market which is projected to reach a valuation of $100 Billion by 2020. But according to researchers, there already exists a better alternative and that is Platelet-Rich Plasma and scores of physicians are now prescribing it as a first line treatment instead of AITs.

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Why Anti-Inflammatory Therapeutics?

One of the reasons why AITs are popular is the belief that most musculoskeletal diseases are due to inflammation. It is believed that inflammation is the cause of injuries and pain. But over the years, numerous studies have shown, rather persuasively, that inflammation is a signaling process used by the body to recruit growth factors and cytokines to the tissue microenvironment. While suppressing the inflammation with drugs interrupts this natural process and provides short term relief to the symptoms, in the long run, it prevents structural healing.

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But the argument among pro-AIT physicians is that they provide the best short term relief. They claim that a short or two of AITs keeps the situation under control and is not a big deal in the larger scheme of things.

Not true. They have pain-relieving properties but not as dramatic as we may think.

First, corticosteroids are not as the ultimate pain-killers and there are other methods far superior.

Second, neither can NSAIDs be considered the most effective pain-killers and that’s a fact.

Third, the immunosuppressive biologics like DMARDS, cytokine-blockers and TNF-blockers are not effective pain-killers anyway.

But they all have one thing in common. And that is, a long-list of side effects.

The Debilitating Effects of AITs

It would have been acceptable if we could just temporarily harness the whatever little pain-relief that AITs offered while we’re looking for a favorable course of action. But that isn’t the case. Studies show that even a single dose of these AITs can lead to unwanted complications. Let’s take a deeper look.

1. Steroids
Steroids are evidently the most destructive ones. Physicians know that they must prescribe steroids very cautiously. But the problem is once they work, patients may prefer them again and again. Especially athletes who just want to get back in the arena for that final game. After all, who wants to sit on the sidelines when life passes by? Just one more time, they’ll say.

But the long term effects are disastrous. Not only are they hard to get off of, the steroids have the ability to kill mesenchymal stem cells, lead to cartilage loss, and are one of the most common causes of secondary osteoporosis. Scores of athletes and weekend warriors have used steroids to temporarily push away pain only to end up in the surgery table a few years later.

2. NSAIDS

NSAIDs are a totally different beast. Medscape reports that more than 70 million of them are prescribed to patients each year in the United States alone. This is in spite of the warning issued by the Arthritis, Rheumatism, and Aging Medical Information System (ARAMIS) against NSAID use.

To the patient, it sounds like a decent proposal – use non-steroidal drug to temporarily alleviate pain. However, the consequences are enormous. In this comprehensively researched article on the Journal of Prolotherapy, the writer calls for a total ban on the use of NSAIDs for joints owing to its potential for degenerating cartilage. This is alarming considering that majority of the NSAIDs are prescribed for joint conditions like arthritis. In another study, use of NSAIDs was shown to have tripled the progression of Knee Osteoarthritis.

Furthermore, even in the 1980s researchers have found that NSAIDs can disrupt intestinal integrity.

3. Biologics

Anti-inflammatory biologics include drugs that block pro-inflammatory cytokines like tumor necrosis factor alpha (TNF) and interlukin-6 (IL-6) as well as conventional disease-modifying antirheumatic drugs (DMARDs). The problem with these drugs is that they suppress the biologic entities responsible for the natural immunity of the body. Applying them to a joint for example, doesn’t limit its effect to that area. Instead, it suppresses these biologic entities THROUGHOUT the body including liver, colon, small intestine, bones, skin and even neurons.

That’s why they have been linked to neurological diseases, and other diseases.

Blocking pro-inflammatory cytokines are definitely a bad idea. For example, the cytokine IL-6, one of the main cytokines targeted by the new generation of Arthritis drugs is a major component of the central nervous system. So is anti-TNF drugs. Blocking these can only lead to adverse events in the long term elsewhere in the body.

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Can PRP Disrupt The Anti-Inflammatory Therapeutics Market?

Although not immediately evident, the trend for these Anti-inflammatory Therapeutics are actually going down. As researchers discover more serious side effects, the market will start shifting to more natural solutions like Platelet-Rich Plasma. In fact, it’s already happening as we speak. Even without the support of insurance companies, more and more people are opting for PRP instead of AITs. That means people are willing to pay out-of-pocket for PRP instead of accepting free drugs. In other words, the downward trend for AITs has begun.

Patients and physicians are learning the hard way that SUPPRESSION OF INFLAMMATION DOES NOT EQUAL TO HEALING.

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On the other hand, the trend for Platelet-Rich Plasma is climbing organically.

Here’s Allen Mishra’s tweet about PRP’s Google trends. Alan is the founder of the Biologic Orthopedic Society that has over 6,500 members in Linkedin.

Independent research is also catching up with Platelet-Rich Plasma. It has proved so far that PRP is far superior for:

1. Chronic low back pain

The study shows that sacroiliac joint (SIJ) injection of Platelet-Rich Plasma has a longer-lasting effect on pain than steroids. And the difference is HUGE. While efficacy of steroids was only 25% at 3 months, it was 90% for PRP.

2. Tennis Elbow

In this study, the steroids were only able to suppress symptoms for recalcitrant lateral epicondylitis, while PRP was able to biologically heal the lesion. Furthermore, the steroids caused further tendon degeneration. Another study proved that patients who had PRP shows better pain and functional improvements than patients who had corticosteroid injection.

3. Plantar fasciitis

This randomized, blinded study concluded that PRP delivered at least the same pain-relief results as steroids. Other researchers have concluded that PRP is actually more effective than steroid injection in terms of pain and functional results. Another study also proved that PRP was more effective and durable than cortisone for plantar fasciitis. Yet another British study also pointed out that PRP injections are superior to corticosteroid injections.

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4. Knee Osteoarthritis

The study above showed that intra-articular PRP injections are better than HA, ozone, and corticosteroids. Another study recently proved that PRP injections are better than Hyaluronic Acid for knee osteoarthritis.

5. Rotator Cuff Tears

This study proved that Platelet-Rich Plasma injections show benefit earlier than cortisone injections for rotator cuff tears. Another similar study also found that a single dose of PRP is better than steroid for Shoulder impingement syndrome.

Why PRP Is Actually Good For Both Patient And Physician

As you can see, the reason why more and more physicians and patients favor Platelet-Rich Plasma over Anti-inflammatory Therapeutics is that PRP not only eliminates the symptoms (pain and function) but it actually heals biologically. Yes, of course, the manufacturers of the conventional drugs would love you to believe that their billion-dollar-research-backed miracle drug is VASTLY superior to the autologous Platelet-Rich Plasma that can be produced within 10-20 minutes in a small clinic. But what we’ve seen is quite the opposite.

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One of the early pioneers of Platelet-Rich Plasma, an orthopedic surgeon Dr. Allan Mishra, M.D., says, that soon this biologic tool would be “safe, simple to use, inexpensive, and available immediately at the point of care.”

And that requires a tipping point in its adoption by physicians. It’s already accelerating at a good pace.

Dr. Mishra goes on to say that, “chronic tendinopathy is the most common indication for applying PRP in my practice. I have used the treatment for tennis elbow, patellar tendinosis, partial Achilles tendon tears and occasionally partial rotator cuff tears as a stand-alone treatment. I also now routinely augment all of my Achilles and patellar tendon repairs with PRP. And I am considering augmenting my arthroscopic rotator cuff repairs as well with PRP. For nonunions or difficult fractures, I combine PRP with bone grafting.”

For the patients, Platelet-Rich Plasma has been helping them avoid surgery for years now. See the videos below for actual testimonials from real patients.

Here’s another patient’s story of how PRP helped avoid surgery.

“When I tore my rotator cuff in 2008, I had conventional laparoscopic surgery to repair it. The outcome was excellent, but the recovery was long and horrible. The orthopedist wouldn’t let me drive for six weeks, or run, swim or lift weights for three months. I suffered through weeks of torturous physical therapy. It was nearly six months before I felt normal again.”

And the patient vowed to never go through that ever again.

Unfortunately, the patient suffered another injury in 2014.

But this time decided to try Platelet-Rich Plasma instead.

The patient said, “I had the first PRP injection on Oct. 23. It was painful, and the aching persisted for about 36 hours. I had one bad night, followed by an uncomfortable day. After that, the pain stopped. Still, my doctor advised me to baby the shoulder — to use my other arm when holding a dog leash and to skip swimming and weights for two weeks. Running was fine. He also recommended physical therapy after two weeks.”

The patient reported that by February 2015, the shoulder was 80% healed. The doctor advised the patient to have a second PRP injection to heal the remaining 20%.

Here’s what the patient said:

“I had [the second injection] on March 4. When I returned to see [the doctor] on April 12, I was feeling pretty good. No pain, no problems. He rolled in the ultrasound machine, and I was not surprised by the results.”

Watch this second video for another excellent patient story.

Get Started On Platelet-Rich Plasma Now

The best way to start making a big difference in your patients, especially if you’re an orthopedic surgeon, rheumatologist or any kind of pain management specialist, is to get going with Platelet-Rich Plasma. Don’t just have it as a back up treatment that you can try when things don’t go well. Instead, it can be used as a standard first-line treatment for musculoskeletal issues.

Give it a serious consideration.

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We can guarantee that once you start offering Platelet-Rich Plasma, you’ll end up prescribing less and less Anti-Inflammatory Therapeutics and more and more Platelet-Rich Plasma. And it will have a tremendous impact on the lives of your patients. We want to see a world where the “replacement surgeries” are a thing of the past.

And Platelet-Rich Plasma can make it happen.

Give us a call if you need more information. We can be reached at (844) 377-7787 or email via hello@drprpusa.com. Or you can order a Platelet-Rich Plasma kit online and try it in your practice.

Together, let’s welcome the Anabolic Era of Medicine.

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Ovarian-Rejuvenation-Platelet-Rich-Plasma-PRP-Injections
This Company Reverses Menopause With PRP Injections

Infertility doesn’t just affect a woman’s capacity to give birth. It also crushes her hormone levels and her emotional ecosystem. So when you hear the statistics that say one in eight women are clinically infertile, that’s a big hole in society as a whole. The lack of simple treatments for fertility correction hasn’t helped the situation either. But that may just change in the near future. Right now, one company is conducting a clinical trial to prove how simple it can be to regenerate ovaries and even reverse menopause. All it takes is a Platelet-Rich Plasma Injection directly into the ovaries. The results from this trial could change the lives of thousands of women worldwide.

Validation of An Idea Whose Time Has Come

Although menopause and infertility are two separate issues altogether, they’re both a function of a healthy ovary. The healthier the ovary, the less chances of menopause and infertility. Platelet-Rich Plasma has long proven it’s chops as a basic regeneration material capable of restoring tissues to its healthy state. So if the simple PRP injections can restore hair follicles, manage wounds, heal ligaments, repair joints, restore spinal discs and even regenerate bones, can it also be used to rejuvenate women’s ovaries? We have to thank researchers in Greece who’d popularized this novel idea starting in 2015.

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It All Started In 2006

Traditionally, women are thought to have born with a fixed number of eggs. And for long, the scientists believed that the “natural” course would be for the eggs to get depleted over time causing women to start producing lower and lower quantities of estrogen, the primary female sex hormone. Once the eggs are depleted, they enter menopause and lose their ability to conceive. But a study in 2006 shattered this paradigm. It revealed an interesting phenomenon in female mice where the mice continued producing eggs long after menopause. The key idea this research put forth was that infertility was not a function of “running out of eggs.” Instead, it’s a direct consequence of an ovary which had become unhealthy.

That opened up possibilities in the mind of Dr. Jonathan Tilly, who had conducted the research on female mice, and he became determined to find a way to “revive” ovaries. Then one fine day, he heard of a research where women who’d received bone-marrow transplants mysteriously had regained their fertility. The rest as they say is history.

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The Power Of Growth Factors

It didn’t take long for Dr. Tilly to discover that it was the growth factors in bone marrow that was rejuvenating the ovaries –
the same growth factors that were available in Platelet-Rich Plasma. But for some strange reason, he did not follow up on that route with ovarian rejuvenation. His company, OvaScience, instead pursued its EggPC IVF method called Augment – which is a super complex process of producing healthy eggs with the aid of mitochondria taken from EggPC cells. The procedure has not been a big success and they have since been focussing on other treatments since.

Fast forward to 2015 and there was a Chinese study that established that Platelet-Rich Plasma can indeed rejuvenate ovaries. They demonstrated it on five women with thin uterine linings all of whom were able to conceive babies after a treatment based on the intrauterine infusion of PRP. At about the same time, a Greek fertility clinic began testing this idea much more aggressively and found that rejuvenating ovaries with Platelet-Rich Plasma worked for both women in various stages of menopause as well as those who had uterine complications. They began testing the effects of trans-vaginal ultrasound guided PRP injection into the ovaries of women. The primary researcher behind it is Kostantinos Pantos and he and his team had injected Platelet-Rich Plasma for over 180 women between 34 and 51 years of age and the results have been promising.

“Success In Two-Thirds Of Cases”

According to Dr. Pantos, in about two-thirds of the cases, he’s able to identify changes in hormonal patterns, reactivation of menses and egg production. He says, “Women who have been in menopause, whose ovaries aren’t working, who’ve ceased to produce follicles — they’re ovulating.” Once the women start ovulating, Dr. Pantos then sends them to an In Vitro Fertilization (IVF) center for artificial insemination.

Dr. Pantos and his colleague Dr. Sfakianoudis talks about their patient, a 39-year-old from the Netherlands, who had been slowly entering Menopause and had not had a period in four years. She began menstruating again just a month after the PRP injections to her ovaries. ONE MONTH LATER!

In another case, they reversed menopause in a 45-year-old woman who’d been in menopause for 5 years since the age of 40 with just a simple PRP injection on her ovaries.

After several such cases, the greek doctors became convinced that the same essence of Platelet-Rich Plasma which is capable of regenerating damaged skin, muscles, and bones can also regenerate the ovary.

Back home in New York, the famous fertility clinic headed by Dr. Hugh Melnick, also started offering the ovarian Platelet-Rich Plasma treatment.

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“An Astounding 75% Success Rate In Pre-Clinical Trial”

The discovery of the Greek clinic and its adoption by Dr Melnick, caught the attention of the fertility researcher Dr. E. Scott Sills, who after investigation, became convinced that the treatment holds tremendous potential. Here’s a video of Dr. Sills on The Doctors Show telling the audience why he believes in the treatment.

Dr. Sills then partnered with the Greek clinic to initiate the long process of clinical trials. Pre-clinical studies conducted in late 2015 showed that the treatment was successful in 45 out of 60 women – an astounding 75% success rate and the women were between 45 and 64 years of age.

Their success meant that they could initiate a full clinical trial and found a sponsor – a biomedical company named Ascendance Biomedical headed by Aaron Traywick. Their goal is to publish a peer-reviewed journal. And they got two well-known Berkeley scientists Michael and Irina Conboy to be the advisors for the project. The trials will be headed by Dr. Sills at his Carlsbad, CA based fertility research center, Center for Advanced Genetics.

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Innovium – The World’s First Pilot Trials In Ovarian Rejuvenation

Dr. Sills’ clinical trial, named Innovium, is the world’s first pilot trials in “Ovarian Rejuvenation” using Platelet-Rich Plasma and is limited to just 50 women who’re in menopause and have had at least one failed IVF cycle.  Participants will undergo inter-vaginal ultrasound guided PRP Injections in both of their ovaries and are required to commit to a full IVF session at the facility. By controlling both the Ovarian Rejuvenation therapy and the IVF, Dr. Sills hopes to increase the success rates dramatically.

Managing Director Aaron Traywick has another interesting take on their clinical trials. He says:

“The goal of the trial is not to prove that we can reverse menopause, because over and over again in our treatments, we know that this is the result. We also know that the treatment triggers a whole body response that restores hormones to the levels of youth. Now, we want to see if the rejuvenation is a permanent one, and if we have discovered a connection between the loss of fertility and the damaging effects of aging in the body.”

So the big picture here is the possibility that Platelet-Rich Plasma Injections can reverse the effects of aging. Very promising.

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Restores Hormone Levels To The Levels Of Youth

One of the secondary effects of Ovarian Platelet-Rich Plasma treatments is the change in Hormone levels. Dr. Pantos notes that in those women who had a successful outcome, their hormone levels returned to the level of their youth. According to the Innovium team, during the pre-clinical trial on 60 women, the hormones – Luteinizing Hormone (LH), Follicle-Stimulating Hormone (FSH), Estrogen, and Anti-Mullerian Hormone (AMH) – had returned to youthful levels in all 45 patients for whom the treatment was successful.

This is kinda big deal because it means it’s not just about restoring fertility – Ovarian Platelet-Rich Plasma injections can eliminate or reduce the mood swings, memory loss, lack of focus, irritability, weariness, hot flashes, night sweats, stress, anxiety and depression associated with Menopause. Plus, it can also restore the the water-holding ability and elasticity of the skin. Few can argue that this isn’t a remarkable development in modern medicine.

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Significantly Cheaper Than Existing Methods

What’s even more amazing is the fact that Ovarian Platelet-Rich Plasma Injections are relatively cheap compared to other Stemcell-based and mitochondria-supplementing methods which goes for upwards of $24,000, even some going for more than $34,000. At the time of writing, Dr. Hugh Melnick’s clinic charges only $4000 for the treatment and we believe the price will be substantially more cheaper as more and more physicians start offering it. Therefore the outcome of this clinical trial may well redefine the future of Platelet-Rich Plasma and we could not be more excited. That’s why we encourage our physicians friends to get on board as soon as possible so they can contribute to the development of this novel procedure.

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Another Trial By University of California San Francisco

This isn’t the only clinical trial either. There is another one by UCSF where they are attempting to validate the results of intrauterine Platelet-Rich Plasma injections for overcoming Asherman’s Syndrome and thin endometrial lining. Although the study does not deal with Menopause, it’s a vote of confidence for PRP Injection’s ability to rejuvenate ovarian tissues.

Get On The Bandwagon

The future of Platelet-Rich Plasma is only looking brighter. Right now, with all these wonderful research going on, those who sit on the sidelines refusing to enter the field and start scoring with Platelet-Rich Plasma are going to miss out. But for those believers, there couldn’t be any time more perfect than now. You could be one of the pioneers of this treatment – and who knows, perhaps you’ll be discovering new uses of PRP Injections. This is a treatment which is defined by its simplicity and low set up cost. All you need is a centrifuge and a PRP Kit. Start offering Platelet-Rich Plasma treatments today. And yours could be one of those pioneering medical centers in this field.

PRP INJECTIONS MEDICAL PRACTICE
Why Add PRP Injections To Your Medical Practice? [Infographic]

Many physicians we know claim that PRP Injections have saved their practice. Some of them even say that PRP helped them fall in love with medicine again. Because for the first time in modern medical history, we have a treatment that’s 100% autologous and natural with zero side effects that can aid healing for a variety of medical conditions. Nothing else comes close.

PRP INJECTIONS MEDICAL PRACTICE

While the above is a solid reason for you to start offering Platelet-Rich Plasma in your practice, there are a few other reasons too. Let’s go through them.

  1. It’s extremely simple procedure – and easy to get started: If you choose us, for less than $3000 investment, you can get started with Platelet-Rich Plasma (enough for your first 10 treatments). Plus we’ll train you on everything you’ll need to know as well as provide marketing support.
  2. It’s not just a fad – this treatment is here to stay: For those who’re choosing to “wait and see,” Platelet-Rich Plasma is showing no signs of slowing down. The PRP market is expected to hit about $452 million dollars in 2024. That’s a 12.5% compounded annual rate of growth from just $160 million dollars in 2015.
  3. Your patient satisfaction will skyrocket: In certain categories, the satisfaction rate for patients who’ve gotten PRP treatments is as high as 95%. The treatments surprise the patients with the results – most of them can’t believe they can have a genuine reversal of their condition with such a simple, non-invasive and no-down-time procedure as PRP.

Right now, the time is ripe for you to become a Platelet-Rich Plasma Specialist in your field. There is much research to be done in multiple aspects of PRP treatments ranging from research around combining PRP with other treatments and the composition of PRP itself. Since there is no standard in this, you’ll be creating the standards yourself.

We need you to be the pioneer in this field. Platelet-Rich Plasma, literally, is a turning point in American medical history. And we don’t want you to miss it.

Here’s an infographic that we’ve made as a reminder to this fact:

Infographic: Why Add PRP To Your Medical Practice?

PRP Injections Why Should You Add Them

A great variety of treatments with just one tiny investment

The beauty of Platelet-Rich Plasma is that it has become virtually indispensable in almost all fields of practice. Urology, sports medicine, pain management, skin rejuvenation, eye care, spine care, hair care, these are the most prominent fields. And those physicians who’ve embraced PRP Injections are seeing high patient retention rates too.

So are you considering Platelet-Rich Plasma?

PRP INJECTIONS MEDICAL PRACTICE

TOP PRP TREATMENTS DRPRP DOCTORS
Dear Doctor, These 7 PRP Treatments Are Hot In Your State

It takes 15-20 minutes to draw 20cc of the patient’s blood, mix it with a small amount of citrate and spin it using a special prp kit and a matching centrifuge for producing the Platelet-Rich Plasma you need for most PRP treatments.

That’s what it takes to produce a multi-potential healing aid to speed up your patients’ recovery.

And it’s definitely the best free healing agent that contains growth factors, and platelets which stimulate the influx of macrophages, stem cells and other repair cells.

The Advantages of Doing PRP, The Right Way

Of course, you can create your own PRP easily by putting the blood in a test tube and spinning it in a generic table top centrifuge and no one can tell the difference. However, it may not have any platelets and probably no tissue healing proteins.

If you do it right way, using the right equipment, you can generate PRP with 7x the normal platelet concentrations. This is called Enhanced PRP. You can also use adipose tissue or collagen fibers to hold the PRP material and form a PRP matrix to amplify the effects.

The 5 Type Of Treatments That Are Hot Right Now

People who are new to Platelet-Rich Plasma may have a hard time believing in the scope of healing it offers. The best 5 treatments are the following:

1. PRP Facial Treatments

A whole lot of skin centers thrive just because they are one of the first ones to offer Platelet-Rich Plasma treatments. This is kind of a treatment that doesn’t need much convincing since there’s no side effects and no down time. Popular prp treatments for face include wrinkle reduction, eye bag and dark circle reduction, skin rejuvenation, gum lift (PRP with collagen sponge is injected after removing stitches in the gum), rosacea reduction, lip augmentation (using a combination of fat and PRP, brought to the limelight by Kylie Jenner and Charlotte Crosby), and vitiligo correction (PRP injection in combination with narrowband-ultraviolet B (NB-UVB) phototherapy improves re-pigmentation).

An especially generic and popular treatment is a combination of Platelet-Rich Plasma and Microneedling. When applied, this novel treatment can produce the effect of botox, lipo or facelift for far less cost.

TOP  PRP TREATMENTS DRPRP DOCTORS

2. PRP Hair Loss Treatments

The growth factors in Platelet-Rich Plasma can reverse non-genetical, early-stage hair loss patterns. There is a huge market for this procedure and very little practitioners offering it. It’s one of the areas for Platelet-Rich Plasma that has a huge unrealized potential. Clients also have seen successful results in cases of thinning hair and even beard regrowth.

TOP  PRP TREATMENTS DRPRP DOCTORS

3. PRP For Arthritis And Cartilage Repair

More than $6.4 billion worth of Arthritis treatments were performed in the US in 2013 alone. That number is poised to hit $9 billion by 2020. And study after study are showing how PRP can not only reduce arthritis symptoms but also regenerate the knee cartilage, something which no other mode of treatments have been able to do.

PRP treatments for Temporomandibular Joint Osteoarthritis (TMJ) is one of the most in-demand ones.

TOP  PRP TREATMENTS DRPRP DOCTORS

4. PRP for Anti-Aging

There are several high end products and complicated procedures that are popular in the Anti-Aging market. None can rival Platelet-Rich Plasma in it’s effectiveness and simplicity. Hence there is a high demand for Anti-Aging-related PRP treatments. PRP combined with Microneedling procedure can be used for acne scars, open pores, stretch marks, hand rejuvenation, Lichen Sclerosus (skin condition in vulva), melasma and breast augmentation.

Another popular treatment is injections of fat mixed with PRP to improve the appearance of cellulite on hip and butt.

5. PRP for Pain Relief And Musculoskeletal Healing

Okay, so this is a very broad category where PRP is considered as the first-line treatment. Most talked about treatments in this category are for Achilles Tendonitis, Rotator Cuff, Tennis elbow, MCL Tear, Meniscus Tear, Plantar Fasciitis, Patellar Tendonitis, Piriformis Syndrome (Severe Buttocks Pain), ACL Tear, Failed Spine Surgery, Back Pain, Lower Back Pain, Hip and Pelvic Disorders, Degenerative Disc Disease, Golfer’s Elbow, Acromio-Clavicular Joint Pain, Labaral Tear, Bursitis, Neuropathic Pain Relief (Nerve Regeneration -Platelet Lysates are used where inflammation is an issue), Spinal Stenosis or Neck Pain, Avascular Necrosis (Osteonecrosis) Or Dying Bones.

Unlike the PRP treatments in the other categories, almost all of these PRP treatments in this category are placed under ultrasound guidance directly onto the affected tissue. Patients often see really good results in as little as two weeks.

TOP  PRP TREATMENTS DRPRP DOCTORS

6. PRP For Infertility

The treatment known as Ovarian Rejuvenation where Platelet-Rich Plasma is directly injected to the patient’s ovaries to reverse menopause or heal fertility issues. This treatment can also result in sexual regeneration. However, this is different from those treatments where PRP is injected into vagina for treating incontinence, looseness, dryness and lack of drive.

Another treatment is for reduction of Vaginal Atrophy symptoms using a combination of Lipofilling and PRP.

TOP  PRP TREATMENTS DRPRP DOCTORS

7. PRP treatments for COPD (Chronic Obstructive Pulmonary Disease)

Recently, physicians are also using PRP for treating lung problems such as allergies, asthma and COPD. The Platelet-Rich Plasma is mixed with with saline and inhaled through the nebulizer for regeneration of lung tissues.

It takes 1-2 months for the treatment to take full effect – but patients are seeing great results. One patient with COPD had his best lung condition in 7 years just 2 months after the treatment. Considering that COPD is a huge issue affecting the lives of more than 700,000 Americans every year, this is major feat.

Honorable mentions

PRP for Dry Eyes: This is one of those health categories where Platelet-Rich Plasma surprised everyone with the results. This treatment is catching up fast although PRP hasn’t become the de-facto treatment.

Erectile Disfunction: This is a widely popular treatment with mixed results. The treatment is popular because of it’s low-risk profile and potential high up side (literally!)

The Future Is Looking Bright

In summary, the trend for PRP is strong – and is here to stay. It’s not a one-trick pony. After all, it’s a natural healing mechanism. And the whole procedure takes a maximum of 60 minutes for the patients with zero recovery time.

That’s why thousands of clinics and major medical establishments are making it a standard treatment for many of the medical conditions they specialize in.

We are already seeing huge the demand for PRP treatments. We receive enquiries from patients who can’t find doctors doing PRP treatments in their area – and often times they are willing to travel for the treatments. This shows how bad the demand is.

So are you offering PRP treatments or are you missing out on this easy, life-saving treatment?

Jump on board with the best PRP Treatment accessories. 🙂

Platelet-Rich Plasma Injections Protocol
Platelet-Rich Plasma Injections: Protocol Guide

Almost all sports medicine doctors would agree that there’s no harm in trying Platelet Rich Plasma Injections (PRP Injections) for their patients. After all, there are hundreds of thousands of cases of positive results. All it needs is research to prove it’s worth. Currently there are many independent researches going on from private funding like the one conducted by Dr. Kimberly G. Harmon M.D., director of the Primary Care Sports Medicine fellowship at University of Washington. She just recently received a gift to support her research from UW alumni who I’m guessing firmly believes in Platelet-Rich Plasma (PRP).

While the process of extracting PRP is fairly simple — there are many variants as long as platelets are above baseline levels with at least seven growth factors — many physician are still unsure about what they can and can’t do when it comes to this marvelous procedure. So today I want to take the time to shine light on the fine print.

Platelet-Rich Plasma Injections Protocol

PRP: Protocols, Technique and Safety Endorsements

Protocol/Technique

Usually, the procedure requires the physician/surgeon and an assistant or two to help with the preparation of graft, the maintenance of sterile technique and saving the ultrasound images (if relevant).

Pre-Procedure Considerations

  • There should always be a specific indication associated with a physical exam with confirmed imaging studies such as an ultrasound, Cat Scan, or an MRI before treatment.
  • Proper patient education and a discussion must be had with the patient as well as a signed informed consent prior to the procedure.
  • Contraindications reviewed prior to procedure.

Graft Preparation

  • The patient is to positioned in a comfortable seated or reclining position.
  • Sterile single needles and syringes must be used with proper handling and disposal.
  • Using an aseptic procedure, the proper amount of blood is then drawn from the vein for the PRP procedure.
  • If the blood cannot be obtained from the site the first, time a new site must be used to prevent early activation.
  • Using a sterile technique, transfer the tube of venous blood to the centrifuge. Platelet Rich Plasma should be acquired using a separating device created for autologous blood. Preference is always given to a closed system that will prevent exposure of the blood and its cellular modules to the open air, and permits minimal use of the tissue.

Image Guidance PRP Therapy

  • Real time imaging guidance using ultrasound CT, or fluoroscopy should always be used when performing a PRP injection.
  • If ultrasound is going to be used, the subsequent considerations need to be decided on in advance: For lengthy procedures, PRP injections near the spine and intra-articular injections sterile gel is recommended.
  • Always use sterile probe covers. Cleansing the probe before and after the PRP procedures and observance to sterile technique is sufficient.
  • Guided images and ineradicable markings of the site of the probe position and the needle entry always needs to be made before cleaning the skin where the probe and needle will be inserted.
  • Always apply a bandage or a dressing after the procedure to protect the entry site from germs.

Post-Injection

  • The patient should be monitored for any post PRP procedure complications such as vaso-vagal.
  • The patients should be given their post procedure directions and precautions and any questions should be answered before they leave, they should also have emergency contact information.
  • Patients should also be instructed about the immobilization and any post procedure activity that is allowed and/or not allowed.
  • Post PRP procedure pain prescriptions need to be given to the patient before discharge and any questions they may have about the medication(s) should be answered at this time. The patient also needs to be instructed to avoid NSAIDs till they have healed, are pain free, has full function has returned to the area being treated (or at least to the limited area being treated.
  • Per OSHA guidelines contaminated areas must be disinfected, before the next patient uses the room (area.)
  • The PRP procedure must be documented in detail, which includes a procedure note that contains the following information: date, pre and post procedure diagnosis, name of the procedure, physician/surgeon(s), any assistants, whether or not anesthesia was used, and if so what type, short-term indication of the procedure, a description of the graft preparation, a description of the procedure that includes any/all guidance and instruments used.

Platelet-Rich Plasma Injections Protocol

Follow-up

  • Patients are normally re-examined in 2-6 weeks after the PRP procedure to follow-up on pain, use, the injection site and to discuss any concerns and any future course of action.
  • The patient response of the treatment should be recorded using authenticated outcome measures.
  • Any complications responses and all other relevant information should be logged into in the ICMS tracking system.
  • The consideration for another PRP injection should be the center of the discussion and the patient will be able to make a decision based on the outcome.

Safety

  • With every medical procedure universal precautions must be used including before, during and after the procedure.
  • Risk of infection – PRP is antimicrobial and provides effective protection against most bacterial infections except for Klebsiella, Pseudomonas, and Enterococcus.
  • With the graft being made entirely out of autologous it basically eliminates the apprehension for the transmission of disease unless the graft became contaminated.

Risks to Patient from the Procedure

  • Infection
  • Bleeding
  • Nerve damage
  • Pain
  • Lack of result
  • Loss of limb and death are very rare but possible.

Platelet Rich Plasma: Indications 

Musculoskeletal complaints, require a complete history and exam to find a diagnosis.  Often times, diagnostic studies may be needed and reviewed to understand why prior treatments failed. PRP is usually considered an optional treatment for chronic and subacute conditions.  Commonly, healing slows down or stops all together at the 6-12 weeks’ period following an acute or traumatic injury.  If the patient has not had any improvement for over the first six weeks, it’s probable the healing period has stopped.

Platelet-Rich Plasma Injections Protocol

Platelet Rich Plasma: Contraindications

  • Septicemia
  •  Platelet dysfunction syndrome
  •  Localized infection at the procedure site
  •  Hemodynamic instability
  •  Critical thrombocytopenia
  •  Patient not willing to take the risks involved with the procedure

Relative Contraindications:

  •  Regular use of NSAIDs within 48 hours of the PRP procedure
  •  HGB of < 10 g/dl
  •  Platelet count of < 105/ul
  •  Systemic use of corticosteroids within 2 weeks
  •  Recent illness or fever
  •  Cancer – particularly hematopoietic or of the bone
  •  HGB < 10 g/dl • Platelet count < 105/ul
  • Corticosteroid injection at treatment site within 1 month
  • Tobacco use
PLATELET-RICH PLASMA TRENDS
Platelet-Rich Plasma Stays Quietly Popular Despite Neglect

Fact: According to research, PRP treatments are one of the most in-demand treatments available in healthcare.

This is impressive considering the following.

  1. PRP is not supported by the medical industry. No big pharma funding on extensive research or marketing. No medical associations lobbying to increase its awareness.
  2. PRP is shunned by the insurance companies. No reimbursements from them. So getting patients to pay is difficult. Especially for a treatment that’s relatively “unproven” like this.
  3. The cost of PRP treatments are actually rising. In 2006, you can get a PRP treatment for $450. Today it costs $800. The cheapest we’ve seen is $650. The prices are still robust as demand keeps up.

However, we believe the best of PRP is not even here yet. We’re just one breakthrough study away from exploding into mainstream hospitals and clinics. We see the biggest growth in Platelet-Rich Plasma happening in Asia.

Strongly based on fundamental healing theory

The growth can be attributed to PRP’s fundamental healing property. More platelets. More growth factors and cytokines. And therefore more healing. It’s as simple as that. And no one can argue this fact.

Our body’s natural healing mechanism operates with 150,000/ul-350,000/ul platelets in blood. Using Platelet-Rich Plasma means this number is amplified by 3X to 5X. How can this be not translated into better healing?

Believe it or not, the best orthopedic doctors use Platelet-Rich Plasma. And do so regularly.

PLATELET-RICH PLASMA TRENDS

PRP can be used to promote healing of injured tendons, ligaments, muscles, and joints, can be applied to various musculoskeletal problems. And they conduct regular studies to test it’s effectiveness.

One landmark study involved double-blind randomized controlled trials to see the effect of PRP on patients with chronic low back pain caused by torn discs. The study outcome says 60% of the patients felt significant improvements.

Some were cured. CURED!

Platelet-Rich Plasma Variants

So far, there are the following type of PRP variants.

  • Plasma Rich in Growth Factors (PRGF)
  • Plasma Rich in Platelets and Growth Factors (PRPGF)
  • Platelet-Rich Plasma (PRP); Platelet Poor Plasma (PPP)
  • Plasma Rich in Platelets and Rich in Leukocytes (LR-PRP)
  • Plasma Rich in Platelets and Poor in Leukocytes (LP-PRP)
  • Platelet-Rich Fibrin Matrix (PRFM)

All of them involve Plasmapherisis — the two stage centrifugation process to separate platelets from blood. However, what happen what happens after that can be different. And the industry hasn’t found it’s middle ground as to which variant to be standardized. We believe the confusion will clear up in 3-5 years.

PLATELET-RICH PLASMA TRENDS

No matter which variant you end up using, the bio-factors at play are the following:

  1. Growth factors: TGF-B, PDGF, IGF-I,II,  FGF,  EGF, VEGF, ECGF
  2. Adhesive proteins: Fibrinogen, Fibronectin, Vitronectin, Thrombospondin-1
  3. Clotting & Anti-Clotting factors: Proteins,  Antithrombin, Plasminogen, Proteases, Antiproteases
How Platelet-Rich Plasma Actually Work

Why is the treatment commonly used for wound healing and pain management? The answer is because the platelets’ main job is to aid coagulation, act as a biological glue and support stem or primary cell migration. In addition, it also helps in restoring hyaluronic acid and accelerates the synthesis of collagen and glycosaminoglycans and increases cartilage matrix.

Not only that, the platelets are delivered in a clot which means it can immediately act as a scaffold to enable the healing process. 95% of the bio-active proteins are released within 1 hour of injecting Platelet-Rich Plasma. The platelets continue to release growth factors for 7-10 days. Thus it’s recommended to re-inject PRP every 7 days.

PLATELET-RICH PLASMA TRENDS

Why are patients coughing up their hard earned money for this?

This reminds me of hundreds of thousands of PRP treatments paid from patient’s own pocket even though they’ve been paying for years to get covered by their respective insurance provider. In 2015, PRP costs were anywhere between $600 and $800 per site per treatment. And most patients go for repeated treatments. So why were they forking up their hard earned money if the treatment was not working? Weren’t there any better alternatives under the “coverage” of their insurance provider? The answer is 1) the treatment works. 2) there’s nothing else out there that’s as natural and side-effect-free as PRP.

Consider the case of osteoarthritis. 27 millions Americans are impacted by it. 33.6% of people older than 65 are victims. All of them experience gradual degeneration of cartilage and bones — they lose roughly 5% cartilage per year. Yet, our medical industry doesn’t have a fix to stop it.

However, when doctors started doing PRP treatments for their osteoarthritis patients, they found a large majority of them had no further cartilage loss.

To me, it means we should make PRP treatments the default first-line treatment for osteoarthritis across the country.

Another huge market is hair loss and cosmetic facial applications. I know there are many people who believe PRP doesn’t work for hair. Here’s what one of the Platelet-Rich Plasma studies found were the effect of the treatment on hair loss.

“Hair loss reduced and at 3 months it reached normal levels. Hair density reached a peak at 3 months (170.70 ± 37.81, P < 0.001). At 6 months and at 1 year, it was significantly increased, 156.25 ± 37.75 (P < 0.001) and 153.70 ± 39.92 (P < 0.001) respectively, comparing to baseline. Patients were satisfied with a mean result rating of 7.1 on a scale of 1-10. No remarkable adverse effects were noted.”

I’ll take that.

That’s me getting PRP for hair. 🙂

PLATELET-RICH PLASMA TRENDS

PRP market is expected to hit $126 million in 2016

That number looks paltry. But that’s an 180% increase over the 2009 figure of  $45 million.

Consider this. Just for osteoarthritis alone, if all the 27 million Americans receive 1 PRP shot a year at a conservative $400 per treatment, it would be a market of $10 billion. And that’s one condition out of the many that Platelet-Rich Plasma injections are proven to work.

Another condition that PRP is known to work very well is Tennis Elbow. It affects on average 1% to 3% of the overall population. That number is as high as 50% among tennis players.

Do the math.

Just getting Platelet-Rich Plasma covered by insurance will unleash the market big time and will help heal millions of patients naturally, more effectively.

Oh ya, that means the insurance companies will have to pay more. Why would they?

HOWEVER, if this treatment could reduce further expensive intervention like surgery then it may actually be a blessing for the insurance guys in terms of savings. One surgery avoided by a patient through right intervention through PRP treatments will save the insurance companies at least $25,000. Now, that’s a win-win for both patients and insurance.

I believe it’s a matter of time before insurance companies start realizing their folly of not supporting this treatment.

PLATELET-RICH PLASMA TRENDS

After all is said and done, it’s still “unproven”

The problem with PRP is that it can be used for just about everything, which is a good problem to have until health care officials (and insurance companies) start realizing that people are going to misuse it.

So it’s classified as unproven. The VAST scope of the treatment calls for urgent structure and guidelines. There are some 20+ conditions where researchers have found it “helps” in one way or another. It’s a daunting task to prove its efficiency in all the areas. Nevertheless, we’ll get there.

Though we’ll need a lot of funding for that.

And yes, we need to standardize the procedure. As well as come up with optimized protocols for each conditions. Someone need to take initiative on that. We’re counting on independent doctors and medical institutions. The big pharma won’t jump in because what’s in it for them, right?

It’s so simple, you’d be an idiot to not try it.

You only need a vacuum blood harvesting tube like what we offer here, a centrifuge with adapter for the tube, pipettes and 10ml ampules of 10% calcium chloride.

The only complexity comes from not following a standard PRP system. Because the final platelet count can depend on a variety of factors. Like initial volume of blood, the technique used and relative concentration of WBC and/or RBC. As well as on the patient’s side, there are factors such as age, growth factor and WBC content.

However, concentration-wise, there’s little confusion as once a sufficiently high range is reached, more doesn’t have any adverse or enhancing effect — it saturates at a certain point. So that’s the minimum. Once you reach that, you’re good. Although the outcome is not always guaranteed to be same, with the right number of platelets, platelet activation and cytokine release, you can get a consistency in your PRP offerings.

There’s still some uncertainty over the number of injections, the timing and delivery method of Platelet-Rich Plasma. But with wide-spread adoption, some kind of structure will emerge.

Let’s hope the first glimpses of it will arrive this year.

Do you know in 2015, the world saw approximately 1 million knee arthroplasties for osteoarthritis? At $25,000 apiece, $25 billion.

How many of these patients had the good fortune of their doctor recommending PRP early on?

PLATELET-RICH PLASMA TRENDS

cortisone and platelet-rich plasma injections
Cortisone & Healing: The Bad Marriage Ends—New Study Reveals Successor

In 1950, Kendall, Hench, and Reichstein received the Nobel Prize for Physiology and Medicine for their discovery of cortisone. No doubt, it was a great step forward in our knowledge of the hormones of the adrenal cortex and their uses in medicine.

Today, cortisone shots is a leading Anti-inflammatory drug given to relieve pain and inflammation, especially for joints—ankle, elbow, hip, knee, shoulder, spine and wrist.

The thing is, even the people who discovered it, knew cortisone is like insulin—it works only so long as it is given to the patient. And more cortisone actually accelerates degeneration of the soft-tissue in the joints. Even though doctors now limit cortisone injections to 3-4 times a year per patient, it’s still causing harm by pulling the plug on body’s own healing mechanism.

Plus, the entire medical community knows that inflammation is a prerequisite for healing. We had briefly discussed this topic before in our blog, but it’s so important a topic that every time there’s a new study against Cortisone, I’m compelled to write.

The #1 Culprit For Joint Replacement Surgeries

Us, Americans do at least a million joint replacement surgeries every year. And one thing that runs common among all who’re having these surgeries is that almost all of them have had Cortisone shots in the past. In fact, Cortisone injections degenerate the joint so fast that joint replacement is inevitable for those who have them repeatedly.

And the #1 reason why people still get a cortisone shot? It’s covered by insurance. And, that way they can make the most of their insurance policies. But eventually, they get a free joint replacement surgery as a bonus too.

Platelet-Rich Plasma Injections: A Superior Alternative?

Latest research confirms Platelet-Rich Plasma as a worthy successor of Cortisone. Here in this research, Cortisone and PRP are compared side-by-side for treating Plantar Fasciitis. 60 heels with intractable plantar fasciitis were given PRP and Cortisone at 3, 6 and 12 months. Immediately after both treatments, patients with Cortisone was only marginally better than the patients with PRP. But in the long run, PRP crushes Cortisone completely. At 12-months, AOFAS score for Cortisone group was 88.5 compared to 75 for the PRP group (the lower the better).

This is the latest in a series of studies showing up over the years showing why PRP is better than Cortisone. Last year, Fox Valley Orthopedics’ Dr. James Sostak appointed PRP Injections as a successor to Cortisone for Tennis Elbow injuries.

“Tennis elbow is an excellent candidate for PRP treatment,” says Dr. Sostak. “A great deal of research suggests that PRP is superior to cortisone treatments, providing better pain relief, faster functional recovery, and helps the damaged tissues to heal.”

Naturally, Cortisone Hates PRP

Cortisone is no doubt powerful. When combined with PRP, it simply overpowers the effects of PRP. Because Cortisone pulls the plug on all healing activities of the body—including the recruitment of immune cells and stem cells. It’s like taking the batteries out of an alarm clock because it’s beeping while ignoring the fact that you’re late.

Hey, we can do better than that. Platelet-Rich Plasma not only accelerates healing, but also induces growth in ligaments, tendons and even cartilages. Plus, it boosts collagen, making skin appear remarkably better.

Platelets A Must For Wound Healing

The growth factors and stem cells that Platelet-Rich Plasma brings to the table are absolutely necessary for healing. Without them, our bodies simply can’t heal. All we’re doing with a PRP Injection is making them available in plenty. So the ligament, the tendon, the knee meniscus, spine disc, or any other sports injury area can be healed quickly.

PRP In Addition To Other Treatments

The wonderful thing about PRP is that it can be used with almost all other remedies other than Cortisone. It can be used with stem cell procedures, physiotherapy, or any other healing modalities that actually enhance healing instead of inhibiting it. This makes PRP a multi-potential blessing—soon it’s going to be a default healing shot for all kinds of injuries.

drprp Platelet-Rich Plasma prp kit samples

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